DL-GLUTAMIC ACID HYDROCHLORIDE

Base Information

• Chemical Name: DL-GLUTAMIC ACID HYDROCHLORIDE
• CAS No.: 15767-75-6
• Molecular Formula: C5H9NO4^.HCl
• Molecular Weight: 183.592
• Hs Code.: 2922499990
• European Community (EC) Number: 239-858-8
• NSC Number: 9239
• DSSTox Substance ID: DTXSID70935774
• ChEMBL ID: CHEMBL1404532
• Mol file: 15767-75-6.mol

Synonyms:DL-Glutamicacid, hydrochloride;Glutamic acid, hydrochloride (9CI);Glutamic acid,hydrochloride, DL- (8CI);

Chemical Property of DL-GLUTAMIC ACID HYDROCHLORIDE

Chemical Property:

• Appearance/Colour: COA
• Vapor Pressure: 2.55E-05mmHg at 25°C
• Boiling Point: 333.8 °C at 760 mmHg
• Flash Point: 155.7 °C
• PSA: 100.62000
• LogP: 0.76540
• Storage Temp.: Sealed in dry,Room Temperature
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 183.0298355
• Heavy Atom Count: 11
• Complexity: 145

Purity/Quality:

99% ^*data from raw suppliers

2-Aminopentanedioicacidhydrochloride 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(CC(=O)O)C(C(=O)O)N.Cl

Technology Process of DL-GLUTAMIC ACID HYDROCHLORIDE

There total 2 articles about DL-GLUTAMIC ACID HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

triethyl 1-(acetylamino)propane-1,1,3-tricarboxylate (6969-27-3) → DL-glutamic acid hydrochloride (15767-75-6)

Guidance literature:

With hydrogenchloride; at 90 - 100 ℃; for 16h;

DOI:10.1021/jo070878+

Reference yield:

triethyl 1-(acetylamino)prop-2-ene-1,1,3-tricarboxylate (94025-12-4) → DL-glutamic acid hydrochloride (15767-75-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / H₂ / Pd on carbon / ethanol / 1 h / 20 - 25 °C / 2585.81 Torr

2: 64 percent / aq. HCl / 16 h / 90 - 100 °C

With hydrogenchloride; hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1021/jo070878+

Reference yield:

DL-glutamic acid hydrochloride (15767-75-6) → D-Glutamic acid (6893-26-1,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6) + L-glutamic acid (56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6)

Guidance literature:

Yield given. Yields of byproduct given;

DOI:10.1021/ja00381a018

upstream raw materials:

triethyl 1-(acetylamino)propane-1,1,3-tricarboxylate

triethyl 1-(acetylamino)prop-2-ene-1,1,3-tricarboxylate

Downstream raw materials:

N-{4-[(2-thioxo-benzothiazol-3-ylmethyl)-amino]-benzoyl}-glutamic acid

l-glutamic acid hydrochloride

D-glutamic acid hydrochloride

D-Glutamic acid