Ioflupane F-18

Base Information

Chemical Name:Ioflupane F-18
CAS No.:186381-69-1
Molecular Formula:C₁₈H₂₃FINO₂
Molecular Weight:430.291
Hs Code.:
UNII:NT4P0L3OCX
Wikidata:Q27896023

Synonyms:Ioflupane F-18;NT4P0L3OCX;(18F)FP-CIT;18F-FP-beta-CIT;UNII-NT4P0L3OCX;186381-69-1;18F-FPCIT;18F-IOFLUPANE;18F-BETA-CIT-FP;18F-CIT-FP;F-18-FPCIT;FP-CIT F-18;18F-FP-.BETA.-CIT;Q27896023;18FLUORINE-N-3-FLUOROPROPYL-2BETA-CARBOMETHOXY-3BETA-(4-IODOPHENYL) NORTROPANE;8-AZABICYCLO(3.2.1)OCTANE-2-CARBOXYLIC ACID, 8-(3-(FLUORO-18F)PROPYL)-3-(4-IODOPHENYL)-, METHYL ESTER, (1R,2S,3S,5S)-;METHYL (1S,3S,4S,5R)-8-(3-FLUORANYLPROPYL)-3-(4-IODOPHENYL)-8-AZABICYCLO(3.2.1)OCTANE-4-CARBOXYLATE

Suppliers and Price of Ioflupane F-18

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Ioflupane F-18

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:430.07829
Heavy Atom Count:23
Complexity:414

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1C2CCC(N2CCCF)CC1C3=CC=C(C=C3)I
Isomeric SMILES:COC(=O)[C@@H]1[C@H]2CC[C@H](N2CCC[18F])C[C@@H]1C3=CC=C(C=C3)I

Technology Process of Ioflupane F-18

There total 5 articles about Ioflupane F-18 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: (1'R,2'S,3'S,5'S)-3'-(4-iodophenyl)-2'-(methoxycarbonyl)spiro[azetidine-1,8'-bicyclo[3,2,1]octan]-1-ium p-toluenesulfonate

: 186381-69-1
[¹⁸F]FP-CIT

Guidance literature:: With (¹⁸F)-fluoride; kryptofix 222 potassium methanesulfonate salt; In ethanol; water; at 100 - 120 ℃; for 0.166667h; Time; Inert atmosphere;

Reference yield:

: (3-methanesulfonyloxypropyl)-2β-carbomethoxy-3β-(4-iodophenyl)tropane

: 186381-69-1
[¹⁸F]FP-CIT

Guidance literature:: With ¹⁸F-fluoride; caesium carbonate; [2.2.2]cryptande; In water; acetonitrile; tert-butyl alcohol; at 95 ℃; for 0.166667h; ion exchange resin Product distribution / selectivity;

Reference yield:

: 186381-39-5
(3-toluenesulfonyloxypropyl)-2β-carbomethoxy-3β-(4-iodophenyl)tropane

: 186381-69-1
[¹⁸F]FP-CIT

Guidance literature:: With ¹⁸F-fluoride; caesium carbonate; [2.2.2]cryptande; In tert-Amyl alcohol; water; acetonitrile; at 95 ℃; for 0.166667h; ion exchange resin Product distribution / selectivity;