4-(3-Methoxyphenyl)pyrrolidin-2-one

Base Information

Chemical Name:4-(3-Methoxyphenyl)pyrrolidin-2-one
CAS No.:38175-34-7
Molecular Formula:C11H13NO2
Molecular Weight:191.23
Hs Code.:2933790090
European Community (EC) Number:860-401-9
DSSTox Substance ID:DTXSID40496983
Mol file:38175-34-7.mol

Synonyms:4-(3-METHOXYPHENYL)PYRROLIDIN-2-ONE;38175-34-7;4-(3'-methoxyphenyl)-2-pyrrolidinone;SCHEMBL1268402;DTXSID40496983;MFCD09955049;AKOS006314439;SB46199;4-(3-methoxy-phenyl)-pyrrolidin-2-one;AS-38288;CS-0308820;EN300-133889;A847667;Z1198266543

Suppliers and Price of 4-(3-Methoxyphenyl)pyrrolidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(3-methoxyphenyl)pyrrolidin-2-one
100mg
$ 220.00

Crysdot
4-(3-Methoxyphenyl)pyrrolidin-2-one 95+%
1g
$ 637.00

Chemenu
4-(3-Methoxyphenyl)pyrrolidin-2-one 95%
1g
$ 601.00

American Custom Chemicals Corporation
4-(3'-METHOXYPHENYL)-2-PYRROLIDINONE 95.00%
5MG
$ 505.41

Total 16 raw suppliers

Chemical Property of 4-(3-Methoxyphenyl)pyrrolidin-2-one

Chemical Property:

Boiling Point:395.105 °C at 760 mmHg
Flash Point:192.753 °C
PSA：38.33000
Density:1.129 g/cm³
LogP:1.62750
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:191.094628657
Heavy Atom Count:14
Complexity:217

Purity/Quality:

97% ^*data from raw suppliers

4-(3-methoxyphenyl)pyrrolidin-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC(=C1)C2CC(=O)NC2

Technology Process of 4-(3-Methoxyphenyl)pyrrolidin-2-one

There total 5 articles about 4-(3-Methoxyphenyl)pyrrolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 38175-34-7
4-(3-methoxyphenyl)pyrrolidin-2-one

Guidance literature:

Reference yield:

: C₁₂H₁₇NO₃

: 38175-34-7
4-(3-methoxyphenyl)pyrrolidin-2-one

Guidance literature:: With sodium hydrogencarbonate; In water; isopropyl alcohol; at 70 ℃; for 16h;
DOI:10.1016/j.bmcl.2018.03.084

Reference yield:

: 38693-90-2
trans-3-(3-methoxyphenyl)acrylic acid methyl ester

: 38175-34-7
4-(3-methoxyphenyl)pyrrolidin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: 1,8-diazabicyclo[5.4.0]undec-7-ene / 17 h / 0 - 20 °C

2: zinc; hydrogenchloride / isopropyl alcohol / 2.5 h / 20 °C

3: sodium hydrogencarbonate / isopropyl alcohol; water / 16 h / 70 °C

With hydrogenchloride; sodium hydrogencarbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; zinc; In water; isopropyl alcohol;
DOI:10.1016/j.bmcl.2018.03.084