methyl 3-(3-methoxyphenyl)acrylate

Base Information

• Chemical Name: methyl 3-(3-methoxyphenyl)acrylate
• CAS No.: 38693-90-2
• Molecular Formula: C11H12O3
• Molecular Weight: 192.214
• Mol file: 38693-90-2.mol

Synonyms:methyl 3-(m-methoxyphenyl)acrylate;(E)-methyl 3-(m-methoxyphenyl)propenoate;methyl (E)-3-(3-methoxyphenyl)acrylate;m-methoxy trans-cinnamic acid methyl ester;(E)-methyl 3-methoxycinnamate;(E)-methyl 3-(3-methoxyphenyl)acrylate;

Chemical Property of methyl 3-(3-methoxyphenyl)acrylate

Chemical Property:

• PSA: 35.53000
• LogP: 1.88140

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of methyl 3-(3-methoxyphenyl)acrylate

There total 32 articles about methyl 3-(3-methoxyphenyl)acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + trans-3-methoxycinnamic acid (6099-04-3,17570-26-2) → trans-3-(3-methoxyphenyl)acrylic acid methyl ester (38693-90-2)

Guidance literature:

With sulfuric acid; for 12h; Heating;

DOI:10.1021/je00054a042

Reference yield: 96.0%

trimethyl phosphonoacetate (5927-18-4) + 3-methoxy-benzaldehyde (591-31-1) → trans-3-(3-methoxyphenyl)acrylic acid methyl ester (38693-90-2)

Guidance literature:

trimethyl phosphonoacetate; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 0.0833333h;

3-methoxy-benzaldehyde; In tetrahydrofuran; at 20 ℃; for 15h;

DOI:10.1002/chem.201301120

Reference yield: 94.0%

3-methoxy-1-iodobenzene (766-85-8) + acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) → trans-3-(3-methoxyphenyl)acrylic acid methyl ester (38693-90-2)

Guidance literature:

With triethylamine; In neat (no solvent); at 120 ℃; for 0.5h; Sealed tube; Inert atmosphere; Green chemistry;

DOI:10.1016/j.tetlet.2015.02.047

upstream raw materials:

trans-3-methoxycinnamic acid

methyl iodide

methanol

(3-methoxyphenyl)propynoic acid methyl ester

Downstream raw materials:

methyl 3-(3-methoxyphenyl)propionate

meso-3.4-bis-(3-methoxy-phenyl)-adipic acid dimethyl ester