Trityl candesartan

Base Information Edit

Chemical Name:Trityl candesartan
CAS No.:139481-72-4
Molecular Formula:C43H34N6O3
Molecular Weight:682.781
Hs Code.:2933990090
European Community (EC) Number:604-140-9
DSSTox Substance ID:DTXSID40437932
Nikkaji Number:J1.640.924C
Wikidata:Q72515532
Mol file:139481-72-4.mol

Synonyms:Trityl candesartan;139481-72-4;2-Ethoxy-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylic acid;2-ethoxy-3-[[4-[2-(1-trityltetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid;2-ethoxy-1-((2'-(1-trityl-1h-tetrazol-5-yl)biphenyl-4-yl)methyl)-1h-benzo[d]imidazole-7-carboxylic acid;Tritylcandesartan;C43H34N6O3;SCHEMBL498030;DTXSID40437932;VBMKOTRJWPIKMG-UHFFFAOYSA-N;BCP12746;MFCD08436154;AKOS015896035;AB44950;AC-1477;AM90290;CS-W006659;DS-1153;(Trityl candesartan)2-Ethoxy-1-[[2-(2-Triphenyl Methyl)-2H-Tetrazole-5-YL](1,1-Biphenyl)-4-YL]Methyl]Benzimidazole-2-Carboxylic Acid;FT-0652450;A807547;J-007282;1H-BENZIMIDAZOLE-7-CARBOXYLIC ACID, 2-ETHOXY-1-[[2'-[1-(TRIPHENYLMETHYL)-1H-TETRAZOL-5-YL][1,1'-BIPHENYL]-4-YL]METHYL]-;2-ethoxy-1-({2'-[1-(triphenylmethyl)-1H-1,2,3,4-tetrazol-5-yl]-[1,1'-biphenyl]-4-yl}methyl)-1H-1,3-benzodiazole-7-carboxylic acid;2-Ethoxy-1-[[(2 inverted exclamation mark -(1-triphenylmethyl-1H-tetrazol-5-yl)biphenyl-4-yl-)methyl]benzimidazole-7-carboxylicacid;2-ethoxy-1-[[2'-(1-triphenylmethyl-1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid;2-ethoxy-1-[[2'-(N-triphenylmethyltetrazol-5-yl)-biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid;2-ethoxy-1-[[2'-(N-triphenylmethyltetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid;2-Ethoxy-1-[[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid;2-ethoxy-1-[{2'-[1-(trityl)-1H-tetrazol-5-yl]-biphenyl-4-yl}-methyl]-1H-benzimidazole-7-carboxylic acid;2-Ethoxy-1-[2'-[1-(triphenylmethyl)-1H-tetrazole-5-yl]-4-biphenylylmethyl]-1H-benzimidazole-7-carboxylic acid;2-Ethoxy-1-{[2'-(1-trityl-1H-tetrazol-5-yl)-4-biphenylyl]methyl}-1H-benzimidazole-7-carboxylic acid;2-ethoxy-1-{[2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid;2-ethoxy-l-[[2'-(N-triphenylmethyl-tetrazol-5-yl) biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid

Suppliers and Price of Trityl candesartan

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-Ethoxy-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylic acid 95+%
250mg
$ 260.00

Matrix Scientific
2-Ethoxy-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylic acid 95+%
1g
$ 559.00

Crysdot
Tritylcandesartan 97%
5g
$ 380.00

Chemenu
2-Ethoxy-1-((2''-(1-trityl-1H-tetrazol-5-yl)-[1,1''-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylicacid 95+%
1g
$ 131.00

Chemenu
2-Ethoxy-1-((2''-(1-trityl-1H-tetrazol-5-yl)-[1,1''-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylicacid 95+%
5g
$ 359.00

American Custom Chemicals Corporation
TRITYL CANDESARTAN 95.00%
1G
$ 327.60

Ambeed
Tritylcandesartan 97%
1g
$ 30.00

Ambeed
Tritylcandesartan 97%
250mg
$ 12.00

Ambeed
Tritylcandesartan 97%
25g
$ 312.00

Ambeed
Tritylcandesartan 97%
5g
$ 93.00

Total 156 raw suppliers

Chemical Property of Trityl candesartan Edit

Chemical Property:

Appearance/Colour:white powder
Vapor Pressure:0mmHg at 25°C
Melting Point:163-165 °C
Refractive Index:1.677
Boiling Point:908.6 °C at 760 mmHg
PKA:2.06±0.10(Predicted)
Flash Point:503.3 °C
PSA：107.95000
Density:1.26 g/cm³
LogP:8.34220
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Heated)
XLogP3:8.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:11
Exact Mass:682.26923897
Heavy Atom Count:52
Complexity:1090

Purity/Quality:

99% ^*data from raw suppliers

2-Ethoxy-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylic acid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NN=NN5C(C6=CC=CC=C6)(C7=CC=CC=C7)C8=CC=CC=C8)C(=O)O
Uses 2-Ethoxy-1-((2''-(1-trityl-1H-tetrazol-5-yl)-[1,1''-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylic Acid can be used as reagent/reactant in preparation of the anti-hypertensive drug candesartan cilexetil. Candesartan analog as angiotensin II antagonist.

Technology Process of Trityl candesartan

There total 15 articles about Trityl candesartan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%