(R)-(-)-2-Methoxy-2-(1-naphthyl)propionic Acid

Base Information

Chemical Name:(R)-(-)-2-Methoxy-2-(1-naphthyl)propionic Acid
CAS No.:63628-26-2
Molecular Formula:C14H14 O3
Molecular Weight:230.263
Hs Code.:2918990090
European Community (EC) Number:672-682-3
UNII:56R63RTD4C
DSSTox Substance ID:DTXSID90433409
Nikkaji Number:J1.328.332J
Wikidata:Q27261424
Mol file:63628-26-2.mol

Synonyms:63628-26-2;(R)-(-)-2-Methoxy-2-(1-naphthyl)propionic Acid;(R)-2-Methoxy-2-(naphthalen-1-yl)propanoic acid;(R)-2-Methoxy-2-naphthalen-1-yl-propionic acid;(2R)-2-methoxy-2-naphthalen-1-ylpropanoic acid;alphaMnp (-)-(R)-form [MI];UNII-56R63RTD4C;56R63RTD4C;2-Methoxy-2-(1-naphthyl)propionic acid, (-)-;R-(-)-2-Methoxy-2-(1-naphthyl)propanoic acid;(2R)-2-Methoxy-2-(naphthalen-1-yl)propanoic acid;(R)-2-mMethoxy-2-(naphthalen-1-yl)propanoic acid;1-Naphthaleneacetic acid, alpha-methoxy-alpha-methyl- (alphaR)-;(R)-2-Methoxy-2-(1-naphthyl)propionic Acid;MFCD03093633;(R)-2-Methoxy-2-(naphthalen-1-yl)propanoicacid;SCHEMBL6120771;DTXSID90433409;(R)-(-)-alpha-Methoxy-alpha-methyl-1-naphthaleneacetic Acid;AMY19785;AKOS015850979;AKOS016006463;SB38061;AS-67087;.ALPHA.MNP (-)-(R)-FORM [MI];CS-0022219;M1366;(-)-2-methoxy-2-(1-naphthyl)propionic acid;(R)-2-Methoxy-2-(1-naphthyl)propanoic acid;(2R)-2-Methoxy-2-(1-naphthyl)propanoic acid;1-Naphthaleneaceticacid,a-methoxy-a-methyl-,(ar)-;A868085;Q27261424;1-NAPHTHALENEACETIC ACID, .ALPHA.-METHOXY-.ALPHA.-METHYL- (.ALPHA.R)-

Suppliers and Price of (R)-(-)-2-Methoxy-2-(1-naphthyl)propionic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-(-)-2-Methoxy-2-(1-naphthyl)propionic Acid
50mg
$ 140.00

TCI Chemical
(R)-(-)-2-Methoxy-2-(1-naphthyl)propionic Acid >99.0%(HPLC)
100mg
$ 303.00

J&W Pharmlab
(R)-2-Methoxy-2-naphthalen-1-yl-propionicacid 97%
5g
$ 1992.00

J&W Pharmlab
(R)-2-Methoxy-2-naphthalen-1-yl-propionicacid 97%
250mg
$ 198.00

J&W Pharmlab
(R)-2-Methoxy-2-naphthalen-1-yl-propionicacid 97%
100mg
$ 149.00

J&W Pharmlab
(R)-2-Methoxy-2-naphthalen-1-yl-propionicacid 97%
50mg
$ 125.00

J&W Pharmlab
(R)-2-Methoxy-2-naphthalen-1-yl-propionicacid 97%
500mg
$ 299.00

J&W Pharmlab
(R)-2-Methoxy-2-naphthalen-1-yl-propionicacid 97%
1g
$ 498.00

Crysdot
(R)-2-Methoxy-2-(naphthalen-1-yl)propanoicacid 95+%
1g
$ 400.00

ChemScene
(R)-2-mMethoxy-2-(naphthalen-1-yl)propanoicacid
1g
$ 499.00

Total 19 raw suppliers

Chemical Property of (R)-(-)-2-Methoxy-2-(1-naphthyl)propionic Acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:108oC
Refractive Index:-100 ° (C=1, MeOH)
Boiling Point:403.571°C at 760 mmHg
PKA:3.59±0.30(Predicted)
Flash Point:154.388°C
PSA：46.53000
Density:1.204g/cm³
LogP:2.78600
Storage Temp.:2-8°C
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:230.094294304
Heavy Atom Count:17
Complexity:289

Purity/Quality:

97% ^*data from raw suppliers

(R)-(-)-2-Methoxy-2-(1-naphthyl)propionic Acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=CC2=CC=CC=C21)(C(=O)O)OC
Isomeric SMILES:C[C@@](C1=CC=CC2=CC=CC=C21)(C(=O)O)OC

Technology Process of (R)-(-)-2-Methoxy-2-(1-naphthyl)propionic Acid

There total 6 articles about (R)-(-)-2-Methoxy-2-(1-naphthyl)propionic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 67246-78-0
(R)-1-phenylethylammonium (R)-2-methoxy-2-(1-naphthyl)propanoate

: 63628-26-2
(R)-α-methoxy-α-methyl-1-naphthaleneacetic acid

Guidance literature:: With hydrogenchloride; enantioselective reaction;
DOI:10.1016/j.tetlet.2014.05.037

Reference yield:

: 220168-00-3
(R)-2-Methoxy-2-naphthalen-1-yl-propionic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester

: 63628-26-2
(R)-α-methoxy-α-methyl-1-naphthaleneacetic acid

Guidance literature:: (R)-2-Methoxy-2-naphthalen-1-yl-propionic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester; With sodium methylate; In methanol;

With sodium hydroxide; In methanol;
DOI:10.1016/S0957-4166(00)00053-7

Reference yield:

: 63628-25-1
rac-2-methoxy-2-(naphthalen-1-yl)propanoic acid

: 63628-26-2
(R)-α-methoxy-α-methyl-1-naphthaleneacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: 46 percent / DCC; DMAP / CH₂Cl₂

2.1: NaOCH₃ / methanol

2.2: aq. NaOH / methanol

With dmap; sodium methylate; dicyclohexyl-carbodiimide; In methanol; dichloromethane; 1.1: Esterification / 2.1: transesterification / 2.2: saponification;
DOI:10.1016/S0957-4166(00)00053-7