2-(4-((1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)oxy)butoxy)-1H-isoindole-1,3(2H)-dione

Base Information

• Chemical Name: 2-(4-((1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)oxy)butoxy)-1H-isoindole-1,3(2H)-dione
• CAS No.: 94464-30-9
• Molecular Formula: C₂₀H₁₆N₂O₆
• Molecular Weight: 380.357
• NSC Number: 101754
• UNII: S4GV5CC6CI
• DSSTox Substance ID: DTXSID20241498
• Wikidata: Q83125012
• Mol file: 94464-30-9.mol

Synonyms:2-(4-((1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)oxy)butoxy)-1H-isoindole-1,3(2H)-dione;94464-30-9;S4GV5CC6CI;UNII-S4GV5CC6CI;NSC101754;NSC 101754;NSC-101754;DTXSID20241498;PHTHALIMIDE, N,N'-(TETRAMETHYLENEDIOXY)DI-;2-[4-(1,3-dioxoisoindolin-2-yl)oxybutoxy]isoindoline-1,3-dione;1H-ISOINDOLE-1,3(2H)-DIONE, 2,2'-(1,4-BUTANEDIYLBIS(OXY))BIS-

Chemical Property of 2-(4-((1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)oxy)butoxy)-1H-isoindole-1,3(2H)-dione

Chemical Property:

• Boiling Point: 573.3°Cat760mmHg
• Flash Point: 300.5°C
• Density: 1.49g/cm³
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 7
• Exact Mass: 380.10083623
• Heavy Atom Count: 28
• Complexity: 561

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C(=O)N(C2=O)OCCCCON3C(=O)C4=CC=CC=C4C3=O

Technology Process of 2-(4-((1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)oxy)butoxy)-1H-isoindole-1,3(2H)-dione

There total 2 articles about 2-(4-((1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)oxy)butoxy)-1H-isoindole-1,3(2H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1,4-dibromo-butane (110-52-1) + N-hydroxyphthalimide (524-38-9) → N,N'-butane-1,4-diyldioxy-bis-phthalimide (94464-30-9)

Guidance literature:

N-hydroxyphthalimide; With sodium hydroxide; Amberlite IRA-400 chloride form;

1,4-dibromo-butane; In tetrahydrofuran; Heating;

DOI:10.1080/00304940709458584

Reference yield:

→ N,N'-butane-1,4-diyldioxy-bis-phthalimide (94464-30-9)

Guidance literature:

N-Hydroxy-phthalimid, Tetramethylenbromid, Triethylamin, in Dimethylformamid, 25grad, 17h;

DOI:10.1021/jo01041a042

Reference yield:

N,N'-butane-1,4-diyldioxy-bis-phthalimide (94464-30-9) → 1,4-bis-(aminooxy)butane (66080-74-8)

Guidance literature:

With hydrogen bromide; In acetic acid;

DOI:10.1021/jo01041a042

upstream raw materials:

1,4-dibromo-butane

N-hydroxyphthalimide

Downstream raw materials:

1,4-bis-(aminooxy)butane