bis(4-acetamidophenyl) 1-(benzyloxycarbonyl-(S)-prolyl)pyrrolidine-2(R,S)-phosphonate

Base Information

Chemical Name:bis(4-acetamidophenyl) 1-(benzyloxycarbonyl-(S)-prolyl)pyrrolidine-2(R,S)-phosphonate
CAS No.:222610-66-4
Molecular Formula:C₃₃H₃₇N₄O₈P
Molecular Weight:648.653
Hs Code.:

Synonyms:bis(4-acetamidophenyl) 1-(benzyloxycarbonyl-(S)-prolyl)pyrrolidine-2(R,S)-phosphonate

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Chemical Property of bis(4-acetamidophenyl) 1-(benzyloxycarbonyl-(S)-prolyl)pyrrolidine-2(R,S)-phosphonate

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Technology Process of bis(4-acetamidophenyl) 1-(benzyloxycarbonyl-(S)-prolyl)pyrrolidine-2(R,S)-phosphonate

There total 2 articles about bis(4-acetamidophenyl) 1-(benzyloxycarbonyl-(S)-prolyl)pyrrolidine-2(R,S)-phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 168553-76-2
4-(Z-(S)-prolyl)aminobutyraldehyde diethyl acetal

: 222610-66-4
bis(4-acetamidophenyl) 1-(benzyloxycarbonyl-(S)-prolyl)pyrrolidine-2(R,S)-phosphonate

Guidance literature:: Multi-step reaction with 2 steps

1: 0.5 N HCl / tetrahydrofuran / 2 h / Ambient temperature

2: AcOH / 2 h / 85 - 90 °C

With hydrogenchloride; acetic acid; In tetrahydrofuran;
DOI:10.1021/jm981033g