2-Fluoro-6-methoxyphenylboronic acid

Base Information

Chemical Name:2-Fluoro-6-methoxyphenylboronic acid
CAS No.:78495-63-3
Molecular Formula:C7H8BFO3
Molecular Weight:169.948
Hs Code.:2931900090
European Community (EC) Number:676-844-4
UNII:AGF9KE4GA6
DSSTox Substance ID:DTXSID80391160
Nikkaji Number:J3.395.560J
Wikidata:Q72474207
Mol file:78495-63-3.mol

Synonyms:2-Fluoro-6-methoxyphenylboronic acid;78495-63-3;(2-fluoro-6-methoxyphenyl)boronic acid;2-fluoro-6-methoxybenzeneboronic acid;MFCD02179483;6-FLUORO-2-METHOXYPHENYLBORONIC ACID;AGF9KE4GA6;Boronic acid, (2-fluoro-6-methoxyphenyl)-;BORONIC ACID, B-(2-FLUORO-6-METHOXYPHENYL)-;(2-Fluoro-6-methyloxyphenyl)boronic acid;B-(2-Fluoro-6-methoxyphenyl)boronic acid;Boronic acid, (2-fluoro-6-methoxyphenyl);UNII-AGF9KE4GA6;SCHEMBL519872;DTXSID80391160;STK695460;(2-fluoro-6-methoxyphenyl)boranediol;2-Fluoro-6-methoxy-phenylboronic acid;2-fluoro-6-methoxyphenyl boronic acid;AKOS004119219;2-fluoro-6-methoxybenzene boronic acid;AB11233;2-fluoro-6-methoxy-phenyl boronic acid;6-fluoro-2-methoxy-phenyl boronic acid;(2-fluoro-6-methyoxyphenyl)boronic acid;2-fluoro-6-methoxy benzene boronic acid;AC-24785;AM806811;AS-15074;BP-12114;SY018043;[2-fluoro-6-(methyloxy)phenyl]boronic acid;CS-0007649;F0941;FT-0641681;EN300-207214;(+/-)-[2-fluoro-6-(methyloxy)phenyl]boronic acid;J-509494;Z1255416081

Suppliers and Price of 2-Fluoro-6-methoxyphenylboronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Fluoro-6-methoxyphenylboronic acid
1g
$ 50.00

TRC
2-Fluoro-6-methoxyphenylboronic acid
5g
$ 80.00

TCI Chemical
2-Fluoro-6-methoxyphenylboronic Acid (contains varying amounts of Anhydride)
5g
$ 90.00

TCI Chemical
2-Fluoro-6-methoxyphenylboronic Acid (contains varying amounts of Anhydride)
1g
$ 29.00

Synthonix
2-Fluoro-6-methoxyphenylboronic acid 97%
5g
$ 20.00

Synthonix
2-Fluoro-6-methoxyphenylboronic acid 97%
1g
$ 15.00

SynQuest Laboratories
2-Fluoro-6-methoxybenzeneboronic acid 99%
100 g
$ 400.00

SynQuest Laboratories
2-Fluoro-6-methoxybenzeneboronic acid 99%
25 g
$ 112.00

SynQuest Laboratories
2-Fluoro-6-methoxybenzeneboronic acid 99%
5 g
$ 32.00

Sigma-Aldrich
2-Fluoro-6-methoxyphenylboronic acid ≥95%
1g
$ 32.50

Total 101 raw suppliers

Chemical Property of 2-Fluoro-6-methoxyphenylboronic acid

Chemical Property:

Vapor Pressure:0.00042mmHg at 25°C
Melting Point:120-125 °C(lit.)
Refractive Index:1.503
Boiling Point:303.1 °C at 760 mmHg
PKA:8.35±0.58(Predicted)
Flash Point:137.1 °C
PSA：49.69000
Density:1.26 g/cm³
LogP:-0.48590
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:170.0550524
Heavy Atom Count:12
Complexity:145

Purity/Quality:

99% ^*data from raw suppliers

2-Fluoro-6-methoxyphenylboronic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi,Xn
Hazard Codes:Xi,Xn
Statements: 36/37/38-20/21/22
Safety Statements: 26-36/37/39-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1=C(C=CC=C1F)OC)(O)O
Uses Reactant for:? ;Preparation of functionally selective allosteric modulators of GABAA receptors1? ;Suzuki cross-coupling reaction2,3? ;Preparation of inhibitors of the checkpoint kinase Wee14 suzuki reaction 2-Fluoro-6-methoxyphenylboronic Acid is a boronic acid derivative known for its pharmacological activity and utility as intermediates in the synthesis of novel non-boron containing compounds, and potential bacterial mutagens.

Technology Process of 2-Fluoro-6-methoxyphenylboronic acid

There total 2 articles about 2-Fluoro-6-methoxyphenylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 150-46-9
triethyl borate

: 456-49-5
1-fluoro-3-methoxybenzene

: 78495-63-3
(2-fluoro-6-methoxyphenyl)boronic acid

Guidance literature:: 1-fluoro-3-methoxybenzene; With n-butyllithium; triethylamine hydrochloride; diisopropylamine; In tetrahydrofuran; hexane; at -70 ℃; for 0.0833333h;

triethyl borate; In tetrahydrofuran; hexane; at -70 ℃; for 0.166667h;

With hydrogenchloride; In tetrahydrofuran; hexane; water;

Reference yield:

: 75626-21-0
C₉H₁₂BFO₃

: 78495-63-3
(2-fluoro-6-methoxyphenyl)boronic acid

Guidance literature:: With hydrogenchloride;
DOI:10.1016/S0960-894X(02)00460-2

Reference yield: 100.0%

: 7-bromo-6-chloro-8-fluoro-3-nitroquinolin-4(1H)-one

: 78495-63-3
(2-fluoro-6-methoxyphenyl)boronic acid

: 6-chloro-8-fluoro-7-(2-fluoro-6-methoxyphenyl)-3-nitroquinolin-4(1H)-one

Guidance literature:: With methanesulfonato(2-dicyclohexylphosphino-2’,6’-di-i-propoxy-1,1’-biphenyl)(2’-methylamino-1,1‘-biphenyl-2-yl)palladium(II); potassium carbonate; ruphos; In 1,4-dioxane; water; at 70 ℃; for 6h; Inert atmosphere;