(E)-2-[(tert-butyldimethylsilyl)methylene]-1-phenyl-N-propylbut-3-en-1-amine

Base Information

Chemical Name:(E)-2-[(tert-butyldimethylsilyl)methylene]-1-phenyl-N-propylbut-3-en-1-amine
CAS No.:1431665-96-1
Molecular Formula:C₂₀H₃₃NSi
Molecular Weight:315.574
Hs Code.:

Synonyms:(E)-2-[(tert-butyldimethylsilyl)methylene]-1-phenyl-N-propylbut-3-en-1-amine

Suppliers and Price of (E)-2-[(tert-butyldimethylsilyl)methylene]-1-phenyl-N-propylbut-3-en-1-amine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (E)-2-[(tert-butyldimethylsilyl)methylene]-1-phenyl-N-propylbut-3-en-1-amine

Chemical Property:

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Technology Process of (E)-2-[(tert-butyldimethylsilyl)methylene]-1-phenyl-N-propylbut-3-en-1-amine

There total 4 articles about (E)-2-[(tert-butyldimethylsilyl)methylene]-1-phenyl-N-propylbut-3-en-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1431665-79-0
(E)-2-[(tert-butyldimethylsilyl)methylene]-1-phenyl-4-(phenylselanyl)-N-propylbutan-1-amine

: 1431665-96-1
(E)-2-[(tert-butyldimethylsilyl)methylene]-1-phenyl-N-propylbut-3-en-1-amine

Guidance literature:: With dihydrogen peroxide; In tetrahydrofuran; at 0 ℃; for 4h; regioselective reaction; Inert atmosphere;
DOI:10.1016/j.tet.2013.03.060

Reference yield:

: 1431665-35-8
tert-butyldimethyl[4-(phenylselanyl)but-1-yn-1-yl]silane

: 1431665-96-1
(E)-2-[(tert-butyldimethylsilyl)methylene]-1-phenyl-N-propylbut-3-en-1-amine

Guidance literature:: Multi-step reaction with 3 steps

1.1: isopropylmagnesium chloride / diethyl ether / 2.5 h / -78 - -50 °C / Inert atmosphere

2.1: 1 h / -50 °C / Inert atmosphere

2.2: Inert atmosphere

3.1: dihydrogen peroxide / tetrahydrofuran / 4 h / 0 °C / Inert atmosphere

With dihydrogen peroxide; isopropylmagnesium chloride; In tetrahydrofuran; diethyl ether;
DOI:10.1016/j.tet.2013.03.060

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 1431665-96-1
(E)-2-[(tert-butyldimethylsilyl)methylene]-1-phenyl-N-propylbut-3-en-1-amine

Guidance literature:: Multi-step reaction with 4 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / -78 °C / Inert atmosphere

1.2: 0.17 h / 0 °C / Inert atmosphere

2.1: isopropylmagnesium chloride / diethyl ether / 2.5 h / -78 - -50 °C / Inert atmosphere

3.1: 1 h / -50 °C / Inert atmosphere

3.2: Inert atmosphere

4.1: dihydrogen peroxide / tetrahydrofuran / 4 h / 0 °C / Inert atmosphere

With n-butyllithium; dihydrogen peroxide; isopropylmagnesium chloride; In tetrahydrofuran; diethyl ether; hexane;
DOI:10.1016/j.tet.2013.03.060