(2S)-1<2-(2-Dimethylaminoethyl)phenyl>-N-ethyl-N-methyl-2-propanamin

Base Information

• Chemical Name: (2S)-1<2-(2-Dimethylaminoethyl)phenyl>-N-ethyl-N-methyl-2-propanamin
• CAS No.: 145388-32-5
• Molecular Formula: C₁₆H₂₈N₂
• Molecular Weight: 248.412
• Mol file: 145388-32-5.mol

Synonyms:(2S)-1<2-(2-Dimethylaminoethyl)phenyl>-N-ethyl-N-methyl-2-propanamin

Chemical Property of (2S)-1<2-(2-Dimethylaminoethyl)phenyl>-N-ethyl-N-methyl-2-propanamin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S)-1<2-(2-Dimethylaminoethyl)phenyl>-N-ethyl-N-methyl-2-propanamin

There total 3 articles about (2S)-1<2-(2-Dimethylaminoethyl)phenyl>-N-ethyl-N-methyl-2-propanamin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

(2S)-2<2(Ethyl-methyl-amino)propyl>-N,N-dimethylphenylacetamid (145388-31-4) → (2S)-1<2-(2-Dimethylaminoethyl)phenyl>-N-ethyl-N-methyl-2-propanamin (145388-32-5)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 55 ℃; for 2h;

DOI:10.1007/BF00811546

Reference yield:

(1R,2S)-1-phenyl-2-(ethylmethylamino)propanol (48141-64-6) → (2S)-1<2-(2-Dimethylaminoethyl)phenyl>-N-ethyl-N-methyl-2-propanamin (145388-32-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 48 percent / xylene / 24 h / 170 °C

2: 91 percent / LiAlH₄ / diethyl ether / 2 h / 55 °C

With lithium aluminium tetrahydride; In diethyl ether; xylene;

DOI:10.1007/BF00811546

Reference yield:

(1R,2S)-N-<(2-Hydroxy-2-phenyl)-1-methyl-ethyl>-N-methylacetamid (2272-83-5) → (2S)-1<2-(2-Dimethylaminoethyl)phenyl>-N-ethyl-N-methyl-2-propanamin (145388-32-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 75 percent / LiAlH₄ / diethyl ether / 2 h / 55 °C

2: 48 percent / xylene / 24 h / 170 °C

3: 91 percent / LiAlH₄ / diethyl ether / 2 h / 55 °C

With lithium aluminium tetrahydride; In diethyl ether; xylene;

DOI:10.1007/BF00811546

upstream raw materials:

(2S)-2<2(Ethyl-methyl-amino)propyl>-N,N-dimethylphenylacetamid

(1R,2S)-1-phenyl-2-(ethylmethylamino)propanol

(1R,2S)-N-<(2-Hydroxy-2-phenyl)-1-methyl-ethyl>-N-methylacetamid