2-methyl-2-propenyl 4'-methyl-5'-phenyl-(2'E,4'E)-pentadienyl sulfide

Base Information

• Chemical Name: 2-methyl-2-propenyl 4'-methyl-5'-phenyl-(2'E,4'E)-pentadienyl sulfide
• CAS No.: 444577-87-1
• Molecular Formula: C₁₆H₂₀S
• Molecular Weight: 244.401
• Mol file: 444577-87-1.mol

Synonyms:2-methyl-2-propenyl 4'-methyl-5'-phenyl-(2'E,4'E)-pentadienyl sulfide

Chemical Property of 2-methyl-2-propenyl 4'-methyl-5'-phenyl-(2'E,4'E)-pentadienyl sulfide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-methyl-2-propenyl 4'-methyl-5'-phenyl-(2'E,4'E)-pentadienyl sulfide

There total 4 articles about 2-methyl-2-propenyl 4'-methyl-5'-phenyl-(2'E,4'E)-pentadienyl sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

3-Chloro-2-methylpropene (563-47-3) + 4-methyl-5-phenyl-(2E,4E)-pentadienyl thioacetate (444578-05-6) → 2-methyl-2-propenyl 4'-methyl-5'-phenyl-(2'E,4'E)-pentadienyl sulfide (444577-87-1)

Guidance literature:

4-methyl-5-phenyl-(2E,4E)-pentadienyl thioacetate; With potassium hydroxide; sodium thiosulfate; In methanol; at 0 ℃; for 0.5h;

3-Chloro-2-methylpropene; In benzene; at 20 ℃; for 1h;

DOI:10.1016/S0040-4020(01)01224-8

Reference yield:

(2E,4E)-ethyl 4-methyl-5-phenylpenta-2,4-dienoate (58550-28-0) → 2-methyl-2-propenyl 4'-methyl-5'-phenyl-(2'E,4'E)-pentadienyl sulfide (444577-87-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 91 percent / DIBALH / hexane / 1 h / 20 °C

2.1: PPh₃; DIAD / benzene / 1 h / 20 °C

3.1: KOH; Na₂S₂O₃*5H₂O / methanol / 0.5 h / 0 °C

3.2: 93 percent / benzene / 1 h / 20 °C

With potassium hydroxide; di-isopropyl azodicarboxylate; diisobutylaluminium hydride; sodium thiosulfate; triphenylphosphine; In methanol; hexane; benzene; 2.1: Mitsunobu reaction;

DOI:10.1016/S0040-4020(01)01224-8

Reference yield:

(2E,4E)-4-methyl-5-phenyl-penta-2,4-dien-1-ol (148601-11-0) → 2-methyl-2-propenyl 4'-methyl-5'-phenyl-(2'E,4'E)-pentadienyl sulfide (444577-87-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: PPh₃; DIAD / benzene / 1 h / 20 °C

2.1: KOH; Na₂S₂O₃*5H₂O / methanol / 0.5 h / 0 °C

2.2: 93 percent / benzene / 1 h / 20 °C

With potassium hydroxide; di-isopropyl azodicarboxylate; sodium thiosulfate; triphenylphosphine; In methanol; benzene; 1.1: Mitsunobu reaction;

DOI:10.1016/S0040-4020(01)01224-8

upstream raw materials:

3-Chloro-2-methylpropene

4-methyl-5-phenyl-(2E,4E)-pentadienyl thioacetate

(2E,4E)-ethyl 4-methyl-5-phenylpenta-2,4-dienoate

(2E,4E)-4-methyl-5-phenyl-penta-2,4-dien-1-ol

Downstream raw materials:

2-methyl-2-propenyl 4'-methyl-5'-phenyl-(2'E,4'E)-pentadienyl sulfone