Technology Process of 2-hydroxy-1,4-benzenedicarboxaldehyde
There total 8 articles about 2-hydroxy-1,4-benzenedicarboxaldehyde which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
trifluoroacetic acid;
In
dichloromethane;
at 0 - 20 ℃;
for 4h;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / -78 - 20 °C / Inert atmosphere
2: pyridinium chlorochromate / dichloromethane / 12 h / 0 - 25 °C
3: trifluoroacetic acid / dichloromethane / 4 h / 0 - 20 °C / Inert atmosphere
With
lithium aluminium tetrahydride; pyridinium chlorochromate; trifluoroacetic acid;
In
tetrahydrofuran; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium carbonate / water / 1 h / 80 °C / Inert atmosphere
1.2: 16 h / 80 °C
2.1: sulfuric acid / 0 °C / Reflux
3.1: di-isopropyl azodicarboxylate / tetrahydrofuran / 1 h / 0 - 25 °C / Inert atmosphere
4.1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / -78 - 20 °C / Inert atmosphere
5.1: pyridinium chlorochromate / dichloromethane / 12 h / 0 - 25 °C
6.1: trifluoroacetic acid / dichloromethane / 4 h / 0 - 20 °C / Inert atmosphere
With
lithium aluminium tetrahydride; di-isopropyl azodicarboxylate; sulfuric acid; sodium carbonate; pyridinium chlorochromate; trifluoroacetic acid;
In
tetrahydrofuran; dichloromethane; water;
