2-Bromo-4,5-difluorophenylacetic acid

Base Information

Chemical Name:2-Bromo-4,5-difluorophenylacetic acid
CAS No.:883502-07-6
Molecular Formula:C8H5BrF2O2
Molecular Weight:251.027
Hs Code.:2916399090
European Community (EC) Number:689-074-9
DSSTox Substance ID:DTXSID70395677
Wikidata:Q72454480
Mol file:883502-07-6.mol

Synonyms:883502-07-6;2-Bromo-4,5-difluorophenylacetic acid;2-(2-bromo-4,5-difluorophenyl)acetic acid;2-Bromo-4,5-difluorophenylaceticacid;MFCD04973423;2-(2-Bromo-4,5-difluorophenyl)aceticacid;SCHEMBL3366555;DTXSID70395677;CL8753;AKOS015890152;AM62279;AC-26165;DS-12962;SY109533;FT-0656111;EN300-1913915;A862232

Suppliers and Price of 2-Bromo-4,5-difluorophenylacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Bromo-4,5-difluorophenylaceticacid
100mg
$ 45.00

TRC
2-Bromo-4,5-difluorophenylaceticacid
1g
$ 75.00

SynQuest Laboratories
2-Bromo-4,5-difluorophenylacetic acid 98%
1 g
$ 56.00

SynQuest Laboratories
2-Bromo-4,5-difluorophenylacetic acid 98%
5 g
$ 172.00

Crysdot
2-(2-Bromo-4,5-difluorophenyl)aceticacid 95+%
10g
$ 243.00

Crysdot
2-(2-Bromo-4,5-difluorophenyl)aceticacid 95+%
25g
$ 567.00

American Custom Chemicals Corporation
2-BROMO-4,5-DIFLUOROPHENYLACETIC ACID 95.00%
5G
$ 1686.30

American Custom Chemicals Corporation
2-BROMO-4,5-DIFLUOROPHENYLACETIC ACID 95.00%
1G
$ 791.18

Ambeed
2-(2-Bromo-4,5-difluorophenyl)aceticacid 97%
1g
$ 40.00

Ambeed
2-(2-Bromo-4,5-difluorophenyl)aceticacid 97%
250mg
$ 22.00

Total 28 raw suppliers

Chemical Property of 2-Bromo-4,5-difluorophenylacetic acid

Chemical Property:

Vapor Pressure:0.000218mmHg at 25°C
Refractive Index:1.549
Boiling Point:313 °C at 760 mmHg
PKA:3.82±0.10(Predicted)
Flash Point:143.1 °C
PSA：37.30000
Density:1.774 g/cm³
LogP:2.35440
Storage Temp.:Sealed in dry,Room Temperature
Water Solubility.:Slightly soluble in water.
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:249.94410
Heavy Atom Count:13
Complexity:201

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-4,5-difluorophenylaceticacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=CC(=C1F)F)Br)CC(=O)O
Uses 2-Bromo-4,5-difluorophenylacetic acid is used as intermediate in organic syntheses.

Technology Process of 2-Bromo-4,5-difluorophenylacetic acid

There total 1 articles about 2-Bromo-4,5-difluorophenylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 883502-07-6
2-(2-bromo-4,5-difluorophenyl)acetic acid

Guidance literature:

Reference yield: 74.0%

: 883502-07-6
2-(2-bromo-4,5-difluorophenyl)acetic acid

: 2-(2-bromo-4,5-difluorophenyl)acetamide

Guidance literature:: 2-(2-bromo-4,5-difluorophenyl)acetic acid; With thionyl chloride; at 50 ℃; for 0.5h;

With ammonium hydroxide; at 20 ℃; for 1h; Cooling with ice;

Reference yield:

: 883502-07-6
2-(2-bromo-4,5-difluorophenyl)acetic acid

: 1017581-66-6
(2-bromo-4,5-difluorophenyl)acetonitrile

Guidance literature:: Multi-step reaction with 2 steps

1.1: thionyl chloride / 0.5 h / 50 °C

1.2: 1 h / 20 °C / Cooling with ice

2.1: pyridine; trifluoroacetic anhydride / tetrahydrofuran / 1 h / -5 - 20 °C

With pyridine; thionyl chloride; trifluoroacetic anhydride; In tetrahydrofuran;