7-formylamino-5-(3-isopropoxyphenyl)-4-methyl-2-(3-phenprop-1-yl)-2-aza-bicyclo[3.3.1]nononane

Base Information

Chemical Name:7-formylamino-5-(3-isopropoxyphenyl)-4-methyl-2-(3-phenprop-1-yl)-2-aza-bicyclo[3.3.1]nononane
CAS No.:913366-37-7
Molecular Formula:C₂₈H₃₈N₂O₂
Molecular Weight:434.622
Hs Code.:

Synonyms:7-formylamino-5-(3-isopropoxyphenyl)-4-methyl-2-(3-phenprop-1-yl)-2-aza-bicyclo[3.3.1]nononane

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Chemical Property of 7-formylamino-5-(3-isopropoxyphenyl)-4-methyl-2-(3-phenprop-1-yl)-2-aza-bicyclo[3.3.1]nononane

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Technology Process of 7-formylamino-5-(3-isopropoxyphenyl)-4-methyl-2-(3-phenprop-1-yl)-2-aza-bicyclo[3.3.1]nononane

There total 1 articles about 7-formylamino-5-(3-isopropoxyphenyl)-4-methyl-2-(3-phenprop-1-yl)-2-aza-bicyclo[3.3.1]nononane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 444904-17-0
(-)-(1R,4S,5S,7R)-5-[3-(1-methylethoxy)phenyl]-4-methyl-2-(3-phenylpropyl)-2-azabicyclo[3.3.1]nonan-7-amine

: 149-73-5
trimethyl orthoformate

: 913366-37-7
7-formylamino-5-(3-isopropoxyphenyl)-4-methyl-2-(3-phenprop-1-yl)-2-aza-bicyclo[3.3.1]nononane

Guidance literature:: (-)-(1R,4S,5S,7R)-5-[3-(1-methylethoxy)phenyl]-4-methyl-2-(3-phenylpropyl)-2-azabicyclo[3.3.1]nonan-7-amine; With hydrogenchloride; In methanol; diethyl ether;

trimethyl orthoformate; for 1.5h; Heating / reflux;

Reference yield: 64.0%

: 913366-37-7
7-formylamino-5-(3-isopropoxyphenyl)-4-methyl-2-(3-phenprop-1-yl)-2-aza-bicyclo[3.3.1]nononane

: 913366-38-8
5-(3-isopropoxyphenyl)-4-methyl-7-methylamino-2-(3-phenprop-1-yl)-2-azabicyclo[3.3.1]nononane

Guidance literature:: 7-formylamino-5-(3-isopropoxyphenyl)-4-methyl-2-(3-phenprop-1-yl)-2-aza-bicyclo[3.3.1]nononane; With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 16h; Heating / reflux;

With sodium hydroxide; water; In tetrahydrofuran; ethyl acetate; for 0.166667h;