1,2-bis(dodecyloxy)-4-iodo-5-(trimethylsilyl)ethynylbenzene

Base Information

• Chemical Name: 1,2-bis(dodecyloxy)-4-iodo-5-(trimethylsilyl)ethynylbenzene
• CAS No.: 923029-82-7
• Molecular Formula: C₃₅H₆₁IO₂Si
• Molecular Weight: 668.858
• Mol file: 923029-82-7.mol

Synonyms:1,2-bis(dodecyloxy)-4-iodo-5-(trimethylsilyl)ethynylbenzene

Chemical Property of 1,2-bis(dodecyloxy)-4-iodo-5-(trimethylsilyl)ethynylbenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-bis(dodecyloxy)-4-iodo-5-(trimethylsilyl)ethynylbenzene

There total 4 articles about 1,2-bis(dodecyloxy)-4-iodo-5-(trimethylsilyl)ethynylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

1,2-bis(dodecycloxy)-4,5-diiodobenzene (181144-60-5) + trimethylsilylacetylene (1066-54-2) → 1,2-bis(dodecyloxy)-4-iodo-5-(trimethylsilyl)ethynylbenzene (923029-82-7)

Guidance literature:

With triethylamine; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; at 20 - 80 ℃; for 4h;

DOI:10.1021/ja0655441

Reference yield:

1,2-bisdodecyloxybenzene (42244-53-1) → 1,2-bis(dodecyloxy)-4-iodo-5-(trimethylsilyl)ethynylbenzene (923029-82-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / iodine; iodic peroxide; acetic acid / H₂SO₄ / H₂O / 6 h / 70 °C

2: 42 percent / Et₃N / Pd(PPh₃)4; CuI / 4 h / 20 - 80 °C

With iodic peroxide; iodine; acetic acid; triethylamine; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sulfuric acid; In water;

DOI:10.1021/ja0655441

Reference yield:

benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9) → 1,2-bis(dodecyloxy)-4-iodo-5-(trimethylsilyl)ethynylbenzene (923029-82-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium carbonate / dimethylformamide / 1 h / 20 °C

1.2: 77 percent / dimethylformamide / 6 h / 80 °C

2.1: 95 percent / iodine; iodic peroxide; acetic acid / H₂SO₄ / H₂O / 6 h / 70 °C

3.1: 42 percent / Et₃N / Pd(PPh₃)4; CuI / 4 h / 20 - 80 °C

With iodic peroxide; iodine; potassium carbonate; acetic acid; triethylamine; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sulfuric acid; In water; N,N-dimethyl-formamide;

DOI:10.1021/ja0655441

upstream raw materials:

1,2-bis(dodecycloxy)-4,5-diiodobenzene

trimethylsilylacetylene

1,2-bisdodecyloxybenzene

benzene-1,2-diol

Downstream raw materials:

3-((4,5-bis(dodecyloxy)-2-((trimethylsilyl)ethynyl)phenyl)-ethynyl)pyridine

2-((4,5-bis(dodecyloxy)-2-ethynylphenyl)ethynyl)pyridine

2,5-Bis((4,5-bis(dodecyloxy)-2-(pyridin-2-ylethynyl)phenyl)-ethynyl)pyrazine

2,3-bis((4,5-bis(dodecyloxy)-2-(pyridin-2-ylethynyl)phenyl)-ethynyl)pyrazine