2,4,5-trichloro-3,6-dimethoxybenzyl bromide

Base Information

• Chemical Name: 2,4,5-trichloro-3,6-dimethoxybenzyl bromide
• CAS No.: 4640-33-9
• Molecular Formula: C₉H₈BrCl₃O₂
• Molecular Weight: 334.424
• Mol file: 4640-33-9.mol

Synonyms:2,4,5-trichloro-3,6-dimethoxybenzyl bromide

Chemical Property of 2,4,5-trichloro-3,6-dimethoxybenzyl bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,4,5-trichloro-3,6-dimethoxybenzyl bromide

There total 4 articles about 2,4,5-trichloro-3,6-dimethoxybenzyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,4,5-trichloro-3,6-dimethoxytoluene (4640-32-8) → 2,4,5-trichloro-3,6-dimethoxybenzyl bromide (4640-33-9)

Guidance literature:

With N-Bromosuccinimide; Perbenzoic acid; In tetrachloromethane; for 1h; Heating;

DOI:10.1007/BF01165028

Reference yield:

3-methyl-phenol (108-39-4) → 2,4,5-trichloro-3,6-dimethoxybenzyl bromide (4640-33-9)

Guidance literature:

Multi-step reaction with 4 steps

1: Cl₂, aq. AcOH

2: SO₂ / aq. ethanol

3: aq. NaOH

4: Br₂ / CCl₄ / Irradiation

With sodium hydroxide; sulfur dioxide; bromine; chlorine; acetic acid; In tetrachloromethane; ethanol;

DOI:10.1016/S0040-4020(01)93878-5

Reference yield:

2-Methyl-1,4-benzoquinone (553-97-9) → 2,4,5-trichloro-3,6-dimethoxybenzyl bromide (4640-33-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 86 percent / Cl₂ / acetic acid / 5 h

2: 88 percent / aq. Na₂S₂O₄ / CHCl₃

3: 92 percent / aq. KOH / tetrahydrofuran / 12 h / Heating

4: 100 percent / N-bromosuccinimide, benzoyl peroxide / CCl₄ / 1 h / Heating

With potassium hydroxide; N-Bromosuccinimide; Perbenzoic acid; sodium dithionite; chlorine; In tetrahydrofuran; tetrachloromethane; chloroform; acetic acid;

DOI:10.1007/BF01165028

upstream raw materials:

2,4,5-trichloro-3,6-dimethoxytoluene

2,3,5-trichloro-6-methyl-1,4-benzoquinone

2-Methyl-1,4-benzoquinone

3-methyl-phenol

Downstream raw materials:

1-(2,4,5-trichloro-3,6-dimethoxybenzyl)-2,5-dimethoxy-3,4-dimethylbenzene

2,4,5-trichloro-3,6-dimethoxybenzyl alcohol

4,7-dimethoxy-6-(2,4,5-trichloro-3,6-dimethoxybenzyl)indanone

1-(2,4,5-trichloro-3,6-dimethoxybenzyl)-3,4-bis(bromomethyl)-2,5-dimethoxybenzene