(2,5-dimethyl-2H-pyrazol-3-yl)carbamic acid 2,2,2-trifluoroethyl ester

Base Information

• Chemical Name: (2,5-dimethyl-2H-pyrazol-3-yl)carbamic acid 2,2,2-trifluoroethyl ester
• CAS No.: 1197480-43-5
• Molecular Formula: C₈H₁₀F₃N₃O₂
• Molecular Weight: 237.182
• Mol file: 1197480-43-5.mol

Synonyms:(2,5-dimethyl-2H-pyrazol-3-yl)carbamic acid 2,2,2-trifluoroethyl ester

Chemical Property of (2,5-dimethyl-2H-pyrazol-3-yl)carbamic acid 2,2,2-trifluoroethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of (2,5-dimethyl-2H-pyrazol-3-yl)carbamic acid 2,2,2-trifluoroethyl ester

There total 1 articles about (2,5-dimethyl-2H-pyrazol-3-yl)carbamic acid 2,2,2-trifluoroethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-Amino-1,3-dimethylpyrazole (3524-32-1) + 2,2,2-trifluoroethyl chloroformate (27746-99-2) → (2,5-dimethyl-2H-pyrazol-3-yl)carbamic acid 2,2,2-trifluoroethyl ester (1197480-43-5)

Guidance literature:

With triethylamine; In acetonitrile; at 20 - 30 ℃;

DOI:10.1016/j.tet.2011.03.101

Reference yield: 75.0%

(2,5-dimethyl-2H-pyrazol-3-yl)carbamic acid 2,2,2-trifluoroethyl ester (1197480-43-5) + 2-amino-1-(4-methylphenyl)ethanol (53360-85-3) → 1-(2,5-dimethyl-2H-pyrazol-3-yl)-3-(2-hydroxy-2-p-tolylethyl)urea (1223271-54-2)

Guidance literature:

In acetonitrile; at 100 ℃; for 4h;

DOI:10.1016/j.tet.2011.03.101

upstream raw materials:

5-Amino-1,3-dimethylpyrazole

2,2,2-trifluoroethyl chloroformate

Downstream raw materials:

1-(2,5-dimethyl-2H-pyrazol-3-yl)-3-(2-hydroxy-2-p-tolylethyl)urea