(3R,7R)-(+)-epi-centrolobine

Base Information

Chemical Name:(3R,7R)-(+)-epi-centrolobine
CAS No.:1202785-01-0
Molecular Formula:C₂₀H₂₄O₃
Molecular Weight:312.409
Hs Code.:

Synonyms:(3R,7R)-(+)-epi-centrolobine

Suppliers and Price of (3R,7R)-(+)-epi-centrolobine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3R,7R)-(+)-epi-centrolobine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3R,7R)-(+)-epi-centrolobine

There total 11 articles about (3R,7R)-(+)-epi-centrolobine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1202785-00-9
(2R,6R)-2-[(4-tert-butyldimethylsilyloxy)phenethyl]-6-[4-(methoxy)phenyl]-tetrahydro-2H-pyran

: 1202785-01-0
(3R,7R)-(+)-epi-centrolobine

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 ℃; Inert atmosphere;
DOI:10.1002/chem.200902053

Reference yield: 70.0%

: 1-(4-hydroxyphenyl)-2-((2R,6R)-6-(4-methoxyphenyl)tetrahydro-2H-pyran-2-yl)ethanone

: 1202785-01-0
(3R,7R)-(+)-epi-centrolobine

Guidance literature:: With hydrogenchloride; palladium 10% on activated carbon; In ethanol; water; ethyl acetate; at 20 ℃; for 10h;
DOI:10.1016/j.tetlet.2015.06.084

Reference yield:

: 24165-60-4
1-(4-methoxyphenyl)but-3-en-1-ol

: 1202785-01-0
(3R,7R)-(+)-epi-centrolobine

Guidance literature:: Multi-step reaction with 9 steps

1.1: tert-butyl methyl ether; Amano Lipase PS-C II / 96 h / 20 °C / Enzymatic reaction

2.1: potassium carbonate / methanol / 20 °C

3.1: Hoveyda-Grubbs catalyst second generation / dichloromethane / 20 °C

4.1: iodine / tetrahydrofuran / 0.75 h / 20 °C

5.1: osmium(VIII) oxide; sodium periodate; 2,6-dimethylpyridine / toluene; 1,4-dioxane; water / 3 h / 0 °C

6.1: tetrahydrofuran / 0 - 20 °C

6.2: 0 - 20 °C

7.1: Dess-Martin periodane / dichloromethane / 4 h / 0 - 20 °C / Inert atmosphere

8.1: platinum(IV) oxide / methanol / 12 h / 20 °C

9.1: hydrogenchloride; palladium 10% on activated carbon / water; ethanol; ethyl acetate / 10 h / 20 °C

With 2,6-dimethylpyridine; hydrogenchloride; platinum(IV) oxide; sodium periodate; osmium(VIII) oxide; Hoveyda-Grubbs catalyst second generation; tert-butyl methyl ether; Amano Lipase PS-C II; palladium 10% on activated carbon; iodine; potassium carbonate; Dess-Martin periodane; In tetrahydrofuran; 1,4-dioxane; methanol; ethanol; dichloromethane; water; ethyl acetate; toluene;
DOI:10.1016/j.tetlet.2015.06.084