1-Boc-Pyrrolidine

Base Information

Chemical Name:1-Boc-Pyrrolidine
CAS No.:86953-79-9
Molecular Formula:C9H17NO2
Molecular Weight:171.239
Hs Code.:29339900
European Community (EC) Number:617-940-8
DSSTox Substance ID:DTXSID60349184
Nikkaji Number:J525.539B
Wikidata:Q72450628
Mol file:86953-79-9.mol

Synonyms:N-Boc-pyrrolidine;N-butyloxycarbonyl-pyrrolidine

Suppliers and Price of 1-Boc-Pyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
N-Boc-
1mg
$ 633.00

Usbiological
N-Boc-
10g
$ 551.00

Usbiological
N-Boc-
25mg
$ 496.00

Usbiological
N-Boc-
500ug
$ 460.00

Usbiological
N-Boc-
25mg
$ 460.00

Usbiological
N-Boc-
2.5mg
$ 460.00

Usbiological
N-Boc
1mg
$ 425.00

Usbiological
N-Boc
2mg
$ 418.00

Usbiological
N-Boc-
100mg
$ 370.00

Usbiological
N-Boc
2mg
$ 368.00

Total 80 raw suppliers

Chemical Property of 1-Boc-Pyrrolidine

Chemical Property:

Vapor Pressure:0.107mmHg at 25°C
Refractive Index:n20/D 1.449(lit.)
Boiling Point:221.414 °C at 760 mmHg
PKA:-1.28±0.20(Predicted)
Flash Point:87.709 °C
PSA：29.54000
Density:1.026 g/cm³
LogP:1.95520
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
Solubility.:Chloroform, Methanol
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:171.125928785
Heavy Atom Count:12
Complexity:166

Purity/Quality:

98% ^*data from raw suppliers

N-Boc- ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCCC1
Uses 1-Boc-pyrrolidine is a boc-protected cyclic amine used as a building block in the preparation of diastereomers by usually undergoing α'-lithiations and electrophilic substitution reactions. N-Boc-pyrrolidine may be used in the synthesis of the following:2-aryl-N-boc-pyrrolidinesscalemic 2-pyrrolidinylcuprates2-alkenyl-N-Boc-pyrrolidines1-deoxycastanosperminemethylphenidate analogues(+)-elaeokanine A

Technology Process of 1-Boc-Pyrrolidine

There total 35 articles about 1-Boc-Pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 123-75-1
pyrrolidine

: 24424-99-5
di-tert-butyl dicarbonate

: 86953-79-9
tert-butyl pyrrolidine-1-carboxylate

Guidance literature:: With 1-methylimidazolium tetrafluoroborate; at 30 - 35 ℃; for 0.0833333h;
DOI:10.1016/j.tetlet.2008.02.126

Reference yield: 97.0%

: 73286-70-1
N-(tert-butoxycarbonyl)-3-pyrroline

: 86953-79-9
tert-butyl pyrrolidine-1-carboxylate

Guidance literature:: With tetrahydroxydiboron; palladium 10% on activated carbon; water; In dichloromethane; at 20 ℃; for 60h; Inert atmosphere;
DOI:10.1021/jacs.6b02132