N-(p-chlorophenylacetyl)-N'-(o-nitrophenyl)-1,3-propanediamine

Base Information

• Chemical Name: N-(p-chlorophenylacetyl)-N'-(o-nitrophenyl)-1,3-propanediamine
• CAS No.: 514225-42-4
• Molecular Formula: C₁₇H₁₈ClN₃O₃
• Molecular Weight: 347.801
• Mol file: 514225-42-4.mol

Synonyms:N-(p-chlorophenylacetyl)-N'-(o-nitrophenyl)-1,3-propanediamine

Chemical Property of N-(p-chlorophenylacetyl)-N'-(o-nitrophenyl)-1,3-propanediamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(p-chlorophenylacetyl)-N'-(o-nitrophenyl)-1,3-propanediamine

There total 1 articles about N-(p-chlorophenylacetyl)-N'-(o-nitrophenyl)-1,3-propanediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

N1-(2-nitrophenyl)propane-1,3-diamine (145315-42-0) + 4-chlorophenacetyl chloride (25026-34-0) → N-(p-chlorophenylacetyl)-N'-(o-nitrophenyl)-1,3-propanediamine (514225-42-4)

Guidance literature:

With sodium hydroxide; In chloroform; for 0.25h;

DOI:10.1055/s-2002-35980

Reference yield:

N-(p-chlorophenylacetyl)-N'-(o-nitrophenyl)-1,3-propanediamine (514225-42-4) → 10-(4-Chloro-phenyl)-3,4-dihydro-2H-1,4a,9-triaza-phenanthrene 9-oxide (90958-97-7)

Guidance literature:

Multi-step reaction with 2 steps

1: ethyl polyphoshate / 5 h / Heating

2: CHCl₃ / 24 h / 20 °C

With ethyl polyphoshate; In chloroform;

DOI:10.1055/s-2002-35980

Reference yield:

N-(p-chlorophenylacetyl)-N'-(o-nitrophenyl)-1,3-propanediamine (514225-42-4) → 2-(4-chloro-benzyl)-1-(2-nitro-phenyl)-1,4,5,6-tetrahydro-pyrimidine

Guidance literature:

With ethyl polyphoshate; for 5h; Heating;

DOI:10.1055/s-2002-35980

upstream raw materials:

N₁-(2-nitrophenyl)propane-1,3-diamine

4-chlorophenacetyl chloride

Downstream raw materials:

10-(4-Chloro-phenyl)-3,4-dihydro-2H-1,4a,9-triaza-phenanthrene 9-oxide