2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)phenoxy]-(2S)-propanoic acid 1,1-dimethylethyl ester

Base Information

Chemical Name:2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)phenoxy]-(2S)-propanoic acid 1,1-dimethylethyl ester
CAS No.:779331-14-5
Molecular Formula:C₂₀H₂₈BF₃O₅
Molecular Weight:416.246
Hs Code.:

Synonyms:2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)phenoxy]-(2S)-propanoic acid 1,1-dimethylethyl ester

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Chemical Property of 2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)phenoxy]-(2S)-propanoic acid 1,1-dimethylethyl ester

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Technology Process of 2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)phenoxy]-(2S)-propanoic acid 1,1-dimethylethyl ester

There total 2 articles about 2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)phenoxy]-(2S)-propanoic acid 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 779331-13-4
2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)phenol

: 68166-83-6
D-lactic acid t-butyl ester

: 779331-14-5
2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)phenoxy]-(2S)-propanoic acid 1,1-dimethylethyl ester

Guidance literature:: With diethyl diazodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃;

Reference yield:

: 779331-14-5
2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)phenoxy]-(2S)-propanoic acid 1,1-dimethylethyl ester

Guidance literature:

Reference yield:

: 779331-14-5
2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)phenoxy]-(2S)-propanoic acid 1,1-dimethylethyl ester

: 877384-03-7
2-[2-borono-4-(trifluoromethyl)phenoxy]-(2S)-propanoic acid

Guidance literature:: 2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)phenoxy]-(2S)-propanoic acid 1,1-dimethylethyl ester; With trifluoroacetic acid; In dichloromethane; for 0.5h;

With hydrogenchloride; water; In acetonitrile; for 1h;

With hydrogenchloride; sodium hydroxide; more than 3 stages;