(E)-3-[dimethyl(phenyl)silyl]-2-methylacrylaldehyde

Base Information

• Chemical Name: (E)-3-[dimethyl(phenyl)silyl]-2-methylacrylaldehyde
• CAS No.: 120315-28-8
• Molecular Formula: C₁₂H₁₆OSi
• Molecular Weight: 204.344
• Mol file: 120315-28-8.mol

Synonyms:(E)-3-[dimethyl(phenyl)silyl]-2-methylacrylaldehyde

Chemical Property of (E)-3-[dimethyl(phenyl)silyl]-2-methylacrylaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-3-[dimethyl(phenyl)silyl]-2-methylacrylaldehyde

There total 4 articles about (E)-3-[dimethyl(phenyl)silyl]-2-methylacrylaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

carbon monoxide (201230-82-2) + Dimethylphenylsilane (766-77-8) + prop-1-yne (74-99-7) → (Z)-3-(Dimethyl-phenyl-silanyl)-2-methyl-propenal (119480-93-2) + (E)-3-[dimethyl(phenyl)silyl]-2-methylacrylaldehyde (120315-28-8)

Guidance literature:

With triethylamine; dodecacarbonyltetrarhodium⁽⁰⁾; In benzene; at 100 ℃; for 2h; under 7355.08 - 22065.2 Torr; Yield given. Yields of byproduct given;

DOI:10.1021/ja00188a074

Reference yield:

C12H16OSi → (E)-3-[dimethyl(phenyl)silyl]-2-methylacrylaldehyde (120315-28-8)

Guidance literature:

With iodine; In benzene; at 22 ℃; for 12h; stereoselective reaction; Darkness; Inert atmosphere;

DOI:10.1021/jacs.1c01135

Reference yield:

Dimethylphenylsilane (766-77-8) → (E)-3-[dimethyl(phenyl)silyl]-2-methylacrylaldehyde (120315-28-8)

Guidance literature:

Multi-step reaction with 2 steps

1: dirhodioum(II)perfluorobutirate / CH₂Cl₂ / reactions of derivatives

2: I₂ / benzene / Ambient temperature

With dirhodium(II) tetrakis(perfluorobutyrate); iodine; In dichloromethane; benzene;

DOI:10.1016/0040-4039(95)01894-N

upstream raw materials:

carbon monoxide

Dimethylphenylsilane

prop-1-yne

(Z)-3-(Dimethyl-phenyl-silanyl)-2-methyl-propenal

Downstream raw materials:

(E)-(R)-3-(Dimethyl-phenyl-silanyl)-4-methyl-hex-4-enoic acid methyl ester

(E)-(R)-4-(Dimethyl-phenyl-silanyl)-3-methyl-but-3-en-2-ol

Acetic acid (E)-(R)-3-(dimethyl-phenyl-silanyl)-1,2-dimethyl-allyl ester

(3S,4E)-Methyl 4-methyl-3-(dinethylphenylsilyl)hexenoate