4-Benzyloxy-N-((3R,4R)-1-benzyl-4-triisopropylsilanyloxy-azepan-3-yl)-benzamide

Base Information

Chemical Name:4-Benzyloxy-N-((3R,4R)-1-benzyl-4-triisopropylsilanyloxy-azepan-3-yl)-benzamide
CAS No.:188308-57-8
Molecular Formula:C₃₆H₅₀N₂O₃Si
Molecular Weight:586.89
Hs Code.:

Synonyms:4-Benzyloxy-N-((3R,4R)-1-benzyl-4-triisopropylsilanyloxy-azepan-3-yl)-benzamide

Suppliers and Price of 4-Benzyloxy-N-((3R,4R)-1-benzyl-4-triisopropylsilanyloxy-azepan-3-yl)-benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-Benzyloxy-N-((3R,4R)-1-benzyl-4-triisopropylsilanyloxy-azepan-3-yl)-benzamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-Benzyloxy-N-((3R,4R)-1-benzyl-4-triisopropylsilanyloxy-azepan-3-yl)-benzamide

There total 11 articles about 4-Benzyloxy-N-((3R,4R)-1-benzyl-4-triisopropylsilanyloxy-azepan-3-yl)-benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6253-27-6
4,5-epoxy-cyclohexene

: 188308-57-8
4-Benzyloxy-N-((3R,4R)-1-benzyl-4-triisopropylsilanyloxy-azepan-3-yl)-benzamide

Guidance literature:: Multi-step reaction with 13 steps

1: Cr-salen complex / 24 h / -10 °C

2: TFA / methanol / Ambient temperature

3: TBHP / Mo(CO)6 / benzene / Heating

4: KH / tetrahydrofuran / 0 °C

5: 94 percent / NaBH₄ / ethanol

6: 1.) H₂O₂, NaHCO₃, 2.) iPrNH₂ / 1.) THF, 2.) benzene, reflux

7: 97 percent / TEMPO, NaOCl / CH₂Cl₂

8: H₂NOH*HCl, pyridine / CH₂Cl₂

9: Et₃N / CH₂Cl₂

10: 1.) TiCl₃(OiPr), 2.) KH / 1.) CH₂Cl₂, rt, 2.) THF

11: 87 percent / AlH₃ / tetrahydrofuran / 0 °C

12: H₂ / PtO₂ / ethyl acetate

13: Et₃N / CH₂Cl₂ / 0 deg C to rt

With pyridine; aluminium hydride; tert.-butylhydroperoxide; 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; sodium tetrahydroborate; titanium(IV) trichloride isopropoxide; hydroxylamine hydrochloride; hydrogen; dihydrogen peroxide; potassium hydride; sodium hydrogencarbonate; isopropylamine; triethylamine; trifluoroacetic acid; platinum(IV) oxide; hexacarbonyl molybdenum; Cr-salen; In tetrahydrofuran; methanol; ethanol; dichloromethane; ethyl acetate; benzene;
DOI:10.1016/S0040-4039(97)00192-5

Reference yield:

: 125356-58-3
(1R,6R)-6-azidocyclohex-3-en-1-ol

: 188308-57-8
4-Benzyloxy-N-((3R,4R)-1-benzyl-4-triisopropylsilanyloxy-azepan-3-yl)-benzamide

Guidance literature:: Multi-step reaction with 11 steps

1: TBHP / Mo(CO)6 / benzene / Heating

2: KH / tetrahydrofuran / 0 °C

3: 94 percent / NaBH₄ / ethanol

4: 1.) H₂O₂, NaHCO₃, 2.) iPrNH₂ / 1.) THF, 2.) benzene, reflux

5: 97 percent / TEMPO, NaOCl / CH₂Cl₂

6: H₂NOH*HCl, pyridine / CH₂Cl₂

7: Et₃N / CH₂Cl₂

8: 1.) TiCl₃(OiPr), 2.) KH / 1.) CH₂Cl₂, rt, 2.) THF

9: 87 percent / AlH₃ / tetrahydrofuran / 0 °C

10: H₂ / PtO₂ / ethyl acetate

11: Et₃N / CH₂Cl₂ / 0 deg C to rt

With pyridine; aluminium hydride; tert.-butylhydroperoxide; 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; sodium tetrahydroborate; titanium(IV) trichloride isopropoxide; hydroxylamine hydrochloride; hydrogen; dihydrogen peroxide; potassium hydride; sodium hydrogencarbonate; isopropylamine; triethylamine; platinum(IV) oxide; hexacarbonyl molybdenum; In tetrahydrofuran; ethanol; dichloromethane; ethyl acetate; benzene;
DOI:10.1016/S0040-4039(97)00192-5

Reference yield:

: (1S,3R,4R)-4-azido-7-oxabicyclo[4.1.0]heptan-3-ol

: 188308-57-8
4-Benzyloxy-N-((3R,4R)-1-benzyl-4-triisopropylsilanyloxy-azepan-3-yl)-benzamide

Guidance literature:: Multi-step reaction with 10 steps

1: KH / tetrahydrofuran / 0 °C

2: 94 percent / NaBH₄ / ethanol

3: 1.) H₂O₂, NaHCO₃, 2.) iPrNH₂ / 1.) THF, 2.) benzene, reflux

4: 97 percent / TEMPO, NaOCl / CH₂Cl₂

5: H₂NOH*HCl, pyridine / CH₂Cl₂

6: Et₃N / CH₂Cl₂

7: 1.) TiCl₃(OiPr), 2.) KH / 1.) CH₂Cl₂, rt, 2.) THF

8: 87 percent / AlH₃ / tetrahydrofuran / 0 °C

9: H₂ / PtO₂ / ethyl acetate

10: Et₃N / CH₂Cl₂ / 0 deg C to rt

With pyridine; aluminium hydride; 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; sodium tetrahydroborate; titanium(IV) trichloride isopropoxide; hydroxylamine hydrochloride; hydrogen; dihydrogen peroxide; potassium hydride; sodium hydrogencarbonate; isopropylamine; triethylamine; platinum(IV) oxide; In tetrahydrofuran; ethanol; dichloromethane; ethyl acetate;
DOI:10.1016/S0040-4039(97)00192-5