(13C₅-ribo)-N₄-benzoyl-5'-O-dimethoxytrityl-2'-O-(t-butyl-dimethyl-silyl)-cytidine

Base Information

• Chemical Name: (13C₅-ribo)-N₄-benzoyl-5'-O-dimethoxytrityl-2'-O-(t-butyl-dimethyl-silyl)-cytidine
• CAS No.: 159496-18-1
• Molecular Formula: C₄₃H₄₉N₃O₈Si
• Molecular Weight: 768.908

Synonyms:(13C₅-ribo)-N₄-benzoyl-5'-O-dimethoxytrityl-2'-O-(t-butyl-dimethyl-silyl)-cytidine

Chemical Property of (13C₅-ribo)-N₄-benzoyl-5'-O-dimethoxytrityl-2'-O-(t-butyl-dimethyl-silyl)-cytidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (13C₅-ribo)-N₄-benzoyl-5'-O-dimethoxytrityl-2'-O-(t-butyl-dimethyl-silyl)-cytidine

There total 11 articles about (13C₅-ribo)-N₄-benzoyl-5'-O-dimethoxytrityl-2'-O-(t-butyl-dimethyl-silyl)-cytidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

tert-butyldimethylsilyl chloride (18162-48-6) + C32(13)C5H35N3O8 (238096-64-5) → (13C5-ribo)-N4-benzoyl-5'-O-dimethoxytrityl-2'-O-(t-butyl-dimethyl-silyl)-cytidine (159496-18-1) + C38(13)C5H49N3O8Si + C44(13)C5H63N3O8Si2

Guidance literature:

With pyridine; silver nitrate; In tetrahydrofuran;

DOI:10.1016/S0040-4020(99)00294-X

Reference yield:

4-N-benzoylcytosine (26661-13-2) → (13C5-ribo)-N4-benzoyl-5'-O-dimethoxytrityl-2'-O-(t-butyl-dimethyl-silyl)-cytidine (159496-18-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.) 1,1,1,3,3,3-hexamethyldisilazane, Me₃SiCl, 2.) trimethylsilyl triflate / 1.) 120 deg C, 2 h, 2.) 1,2-dichloroethane, 65 deg C, 4 h

2: aq. NaOH / ethanol; pyridine / 0.1 h / Ambient temperature

3: pyridine

4: 55 percent / pyridine, AgNO₃ / tetrahydrofuran

With pyridine; sodium hydroxide; chloro-trimethyl-silane; trimethylsilyl trifluoromethanesulfonate; silver nitrate; 1,1,1,3,3,3-hexamethyl-disilazane; In tetrahydrofuran; pyridine; ethanol;

DOI:10.1016/S0040-4020(99)00294-X

Reference yield:

<1',2',3',4',5'-13C5>-N4-benzoylcytidine (159496-12-5) → (13C5-ribo)-N4-benzoyl-5'-O-dimethoxytrityl-2'-O-(t-butyl-dimethyl-silyl)-cytidine (159496-18-1)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine

2: 55 percent / pyridine, AgNO₃ / tetrahydrofuran

With pyridine; silver nitrate; In tetrahydrofuran; pyridine;

DOI:10.1016/S0040-4020(99)00294-X

upstream raw materials:

tert-butyldimethylsilyl chloride

C₃₂⁽¹³⁾C₅H₃₅N₃O₈

4-N-benzoylcytosine

<1',2',3',4',5'-13C5>-N⁴-benzoylcytidine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 159496-18-1 (13C₅-ribo)-N₄-benzoyl-5'-O-dimethoxytrityl-2'-O-(t-butyl-dimethyl-silyl)-cytidine

Send

Send

Metric Ton KG G Pound L ML

Send

Send