2,6-bis-(toluene-4-sulfonyl)-1,2,3,5,6,7-hexahydro-pyrrolo[3,4-f]isoindole

Base Information

• Chemical Name: 2,6-bis-(toluene-4-sulfonyl)-1,2,3,5,6,7-hexahydro-pyrrolo[3,4-f]isoindole
• CAS No.: 38862-04-3
• Molecular Formula: C₂₄H₂₄N₂O₄S₂
• Molecular Weight: 468.598
• Mol file: 38862-04-3.mol

Synonyms:2,6-bis-(toluene-4-sulfonyl)-1,2,3,5,6,7-hexahydro-pyrrolo[3,4-f]isoindole

Chemical Property of 2,6-bis-(toluene-4-sulfonyl)-1,2,3,5,6,7-hexahydro-pyrrolo[3,4-f]isoindole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,6-bis-(toluene-4-sulfonyl)-1,2,3,5,6,7-hexahydro-pyrrolo[3,4-f]isoindole

There total 4 articles about 2,6-bis-(toluene-4-sulfonyl)-1,2,3,5,6,7-hexahydro-pyrrolo[3,4-f]isoindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

toluene-4-sulfonamide (70-55-3) + 1,2,4,5-tetrabromomethylbenzene (15442-91-8) → 2,6-bis-(toluene-4-sulfonyl)-1,2,3,5,6,7-hexahydro-pyrrolo[3,4-f]isoindole (38862-04-3)

Guidance literature:

With sodium hydride; N,N-dimethyl-formamide;

Reference yield:

4,6-bis(chloromethyl)-m-xylene (1585-15-5) → 2,6-bis-(toluene-4-sulfonyl)-1,2,3,5,6,7-hexahydro-pyrrolo[3,4-f]isoindole (38862-04-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.1.2.2-tetrachloro-ethane; chlorine / 100 - 110 °C / Irradiation

2: ethanolic sodium ethylate

With sodium ethanolate; chlorine; 1,1,2,2-tetrachloroethane;

DOI:10.1002/hlca.19470300714

Reference yield:

toluene-4-sulfonamide (70-55-3) + 1,2,4,5-tetra(chloromethyl)benzene (2206-83-9) → 2,6-bis-(toluene-4-sulfonyl)-1,2,3,5,6,7-hexahydro-pyrrolo[3,4-f]isoindole (38862-04-3)

Guidance literature:

With sodium ethanolate;

DOI:10.1002/hlca.19470300714

upstream raw materials:

toluene-4-sulfonamide

1,2,4,5-tetrabromomethylbenzene

1,2,4,5-tetra(chloromethyl)benzene

4,6-bis(chloromethyl)-m-xylene