ethyl 2-(2-(4-bromophenyl)-1,2-dihydro-3-phenylisoquinolin-1-yl)-2-hydroxyacetate

Base Information

Chemical Name:ethyl 2-(2-(4-bromophenyl)-1,2-dihydro-3-phenylisoquinolin-1-yl)-2-hydroxyacetate
CAS No.:1186207-80-6
Molecular Formula:C₂₅H₂₂BrNO₃
Molecular Weight:464.359
Hs Code.:

Synonyms:ethyl 2-(2-(4-bromophenyl)-1,2-dihydro-3-phenylisoquinolin-1-yl)-2-hydroxyacetate

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Chemical Property of ethyl 2-(2-(4-bromophenyl)-1,2-dihydro-3-phenylisoquinolin-1-yl)-2-hydroxyacetate

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Technology Process of ethyl 2-(2-(4-bromophenyl)-1,2-dihydro-3-phenylisoquinolin-1-yl)-2-hydroxyacetate

There total 1 articles about ethyl 2-(2-(4-bromophenyl)-1,2-dihydro-3-phenylisoquinolin-1-yl)-2-hydroxyacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 623-73-4
diazoacetic acid ethyl ester

: 1186207-91-9
4-bromo-N-(2-(phenylethynyl)benzylidene)aniline

: 1186207-80-6
ethyl 2-(2-(4-bromophenyl)-1,2-dihydro-3-phenylisoquinolin-1-yl)-2-hydroxyacetate

Guidance literature:: With dirhodium tetraacetate; water; silver trifluoromethanesulfonate; In dichloromethane; at 20 ℃; for 1h; optical yield given as %de; diastereoselective reaction; Inert atmosphere;
DOI:10.1021/ol902409u