(S)-hydroxymethyl-2,2-dimethyloxazolidine-3-carboxylic acid benzyl ester

Base Information

Chemical Name:(S)-hydroxymethyl-2,2-dimethyloxazolidine-3-carboxylic acid benzyl ester
CAS No.:133464-36-5
Molecular Formula:C₁₄H₁₉NO₄
Molecular Weight:265.309
Hs Code.:

Synonyms:(S)-hydroxymethyl-2,2-dimethyloxazolidine-3-carboxylic acid benzyl ester

Suppliers and Price of (S)-hydroxymethyl-2,2-dimethyloxazolidine-3-carboxylic acid benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(4S)-2,2-Dimethyl-3-N-Cbz-4-(hydroxymethyl)oxazolidine
10mg
$ 45.00

Crysdot
(S)-Benzyl4-(hydroxymethyl)-2,2-dimethyloxazolidine-3-carboxylate 95+%
1g
$ 667.00

Chemenu
(S)-Benzyl4-(hydroxymethyl)-2,2-dimethyloxazolidine-3-carboxylate 95%
1g
$ 630.00

Total 3 raw suppliers

Chemical Property of (S)-hydroxymethyl-2,2-dimethyloxazolidine-3-carboxylic acid benzyl ester

Chemical Property:

Purity/Quality:

99%, ^*data from raw suppliers

(4S)-2,2-Dimethyl-3-N-Cbz-4-(hydroxymethyl)oxazolidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-hydroxymethyl-2,2-dimethyloxazolidine-3-carboxylic acid benzyl ester

There total 4 articles about (S)-hydroxymethyl-2,2-dimethyloxazolidine-3-carboxylic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 133464-35-4
3-benzyl 4-methyl (4R)-2,2-dimethyloxazolidine-3,4-dicarboxylate

: 133464-36-5
(S)-hydroxymethyl-2,2-dimethyloxazolidine-3-carboxylic acid benzyl ester

Guidance literature:: With sodium tetrahydroborate; In tetrahydrofuran; methanol; at 0 ℃; for 1.08333h; Reflux;
DOI:10.1016/j.ejmech.2017.06.022

Reference yield: 73.0%

: 133464-37-6
(4R)-4-formyl-2,2-dimethyloxazolidine-3-carboxylic acid benzyl ester

: 133464-36-5
(S)-hydroxymethyl-2,2-dimethyloxazolidine-3-carboxylic acid benzyl ester

Guidance literature:: With methanol; sodium tetrahydroborate; at 0 - 20 ℃; for 4h;

Reference yield:

: 93204-36-5
(R)-methyl 2-(((benzyloxy)carbonyl)amino)-3-hydroxypropanoate

: 133464-36-5
(S)-hydroxymethyl-2,2-dimethyloxazolidine-3-carboxylic acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: BF₃*Et₂O / acetone

2: NaBH₄ / tetrahydrofuran; methanol

With sodium tetrahydroborate; boron trifluoride diethyl etherate; In tetrahydrofuran; methanol; acetone;
DOI:10.1055/s-2002-35616