tert-butyl(2-((2R,6S)-6-((E)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-methylprop-1-en-1-yl)-4-methylenetetrahydro-2H-pyran-2-yl)ethoxy)diphenylsilane

Base Information

Chemical Name:tert-butyl(2-((2R,6S)-6-((E)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-methylprop-1-en-1-yl)-4-methylenetetrahydro-2H-pyran-2-yl)ethoxy)diphenylsilane
CAS No.:1437312-77-0
Molecular Formula:C₃₃H₄₆O₄Si
Molecular Weight:534.811
Hs Code.:

Synonyms:tert-butyl(2-((2R,6S)-6-((E)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-methylprop-1-en-1-yl)-4-methylenetetrahydro-2H-pyran-2-yl)ethoxy)diphenylsilane

Suppliers and Price of tert-butyl(2-((2R,6S)-6-((E)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-methylprop-1-en-1-yl)-4-methylenetetrahydro-2H-pyran-2-yl)ethoxy)diphenylsilane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl(2-((2R,6S)-6-((E)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-methylprop-1-en-1-yl)-4-methylenetetrahydro-2H-pyran-2-yl)ethoxy)diphenylsilane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl(2-((2R,6S)-6-((E)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-methylprop-1-en-1-yl)-4-methylenetetrahydro-2H-pyran-2-yl)ethoxy)diphenylsilane

There total 6 articles about tert-butyl(2-((2R,6S)-6-((E)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-methylprop-1-en-1-yl)-4-methylenetetrahydro-2H-pyran-2-yl)ethoxy)diphenylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1437313-05-7
(2S,6S)-2-(2-((tert-butyldiphenylsilyl)oxy)ethyl)-6-((E)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-methylprop-1-en-1-yl)dihydro-2H-pyran-4(3H)-one

: 1779-49-3
Methyltriphenylphosphonium bromide

: 1437312-77-0
tert-butyl(2-((2R,6S)-6-((E)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-methylprop-1-en-1-yl)-4-methylenetetrahydro-2H-pyran-2-yl)ethoxy)diphenylsilane

Guidance literature:: Methyltriphenylphosphonium bromide; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 0 ℃; for 0.583333h; Inert atmosphere;

(2S,6S)-2-(2-((tert-butyldiphenylsilyl)oxy)ethyl)-6-((E)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-methylprop-1-en-1-yl)dihydro-2H-pyran-4(3H)-one; In tetrahydrofuran; hexane; at 0 - 45 ℃; for 0.75h; Inert atmosphere;
DOI:10.1002/chem.201202553

Reference yield:

: 1437312-76-9
(2-((2S,4R,6S)-4-bromo-6-((E)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-methyl prop-1-en-1-yl)tetrahydro-2H-pyran-2-yl)ethoxy)(tert-butyl)diphenylsilane

: 1437312-77-0
tert-butyl(2-((2R,6S)-6-((E)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-methylprop-1-en-1-yl)-4-methylenetetrahydro-2H-pyran-2-yl)ethoxy)diphenylsilane

Guidance literature:: Multi-step reaction with 4 steps

1.1: 18-crown-6 ether / toluene / 20 h / 130 °C

2.1: potassium carbonate / methanol; water / 4 h / 20 °C

3.1: Dess-Martin periodane / dichloromethane / 0.5 h / 20 °C

4.1: n-butyllithium / tetrahydrofuran; hexane / 0.58 h / -78 - 0 °C / Inert atmosphere

4.2: 0.75 h / 0 - 45 °C / Inert atmosphere

With n-butyllithium; 18-crown-6 ether; potassium carbonate; Dess-Martin periodane; In tetrahydrofuran; methanol; hexane; dichloromethane; water; toluene;
DOI:10.1002/chem.201202553

Reference yield:

: 1437313-03-5
C₂₉H₄₁BrO₄Si

: 1437312-77-0
tert-butyl(2-((2R,6S)-6-((E)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-methylprop-1-en-1-yl)-4-methylenetetrahydro-2H-pyran-2-yl)ethoxy)diphenylsilane

Guidance literature:: Multi-step reaction with 5 steps

1.1: toluene-4-sulfonic acid / 20 °C

2.1: 18-crown-6 ether / toluene / 20 h / 130 °C

3.1: potassium carbonate / methanol; water / 4 h / 20 °C

4.1: Dess-Martin periodane / dichloromethane / 0.5 h / 20 °C

5.1: n-butyllithium / tetrahydrofuran; hexane / 0.58 h / -78 - 0 °C / Inert atmosphere

5.2: 0.75 h / 0 - 45 °C / Inert atmosphere

With n-butyllithium; 18-crown-6 ether; potassium carbonate; Dess-Martin periodane; toluene-4-sulfonic acid; In tetrahydrofuran; methanol; hexane; dichloromethane; water; toluene;
DOI:10.1002/chem.201202553