1-(2',3'-di-O-benzoyl-β-D-ribofuranosyl)-2-oxo-1,2-dihydropyridine

Base Information

• Chemical Name: 1-(2',3'-di-O-benzoyl-β-D-ribofuranosyl)-2-oxo-1,2-dihydropyridine
• CAS No.: 15354-20-8
• Molecular Formula: C₂₄H₂₁NO₇
• Molecular Weight: 435.433
• Mol file: 15354-20-8.mol

Synonyms:1-(2',3'-di-O-benzoyl-β-D-ribofuranosyl)-2-oxo-1,2-dihydropyridine

Chemical Property of 1-(2',3'-di-O-benzoyl-β-D-ribofuranosyl)-2-oxo-1,2-dihydropyridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2',3'-di-O-benzoyl-β-D-ribofuranosyl)-2-oxo-1,2-dihydropyridine

There total 2 articles about 1-(2',3'-di-O-benzoyl-β-D-ribofuranosyl)-2-oxo-1,2-dihydropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyridinone (5116-31-4) → 1-(2',3'-di-O-benzoyl-β-D-ribofuranosyl)-2-oxo-1,2-dihydropyridine (15354-20-8)

Guidance literature:

With methanol; di(tert-butyl)chlorotinhydroxide dimer; at 66 ℃; for 75h;

DOI:10.1021/jo702249j

Reference yield:

→ 1-(2',3'-di-O-benzoyl-β-D-ribofuranosyl)-2-oxo-1,2-dihydropyridine (15354-20-8)

Guidance literature:

Pyridon-(2)-N-ribofuranosid, Benzoylchlorid, Triphenylmethylchlorid;

DOI:10.1002/ardp.19673001009

Reference yield: 64.0%

1-(2',3'-di-O-benzoyl-β-D-ribofuranosyl)-2-oxo-1,2-dihydropyridine (15354-20-8) + [(dibenzyloxyphosphorylmethyl)benzyloxyphosphinoylmethyl]phosphonic acid methyl ester (1010804-51-9) → 1-(2',3'-di-O-benzoyl-5'-(bis-[(benzyloxyphosphorylmethyl)benzyloxyphosphorylmethyl]methyloxyphosphoryl)-β-D-ribofuranosyl)-2-oxo-1,2-dihydropyridine (1010804-52-0)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 3.5h;

DOI:10.1021/jo702249j

upstream raw materials:

1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyridinone

Downstream raw materials:

1-(2',3'-di-O-benzoyl-5'-(bis-[(benzyloxyphosphorylmethyl)benzyloxyphosphorylmethyl]methyloxyphosphoryl)-β-D-ribofuranosyl)-2-oxo-1,2-dihydropyridine