[(2S,3R)-2-(1,1-Dimethyl-2-phenylsulfanyl-ethyl)-3-methoxy-4-oxo-azetidin-1-yl]-acetic acid

Base Information

• Chemical Name: [(2S,3R)-2-(1,1-Dimethyl-2-phenylsulfanyl-ethyl)-3-methoxy-4-oxo-azetidin-1-yl]-acetic acid
• CAS No.: 86255-87-0
• Molecular Formula: C₁₆H₂₁NO₄S
• Molecular Weight: 323.413

Synonyms:[(2S,3R)-2-(1,1-Dimethyl-2-phenylsulfanyl-ethyl)-3-methoxy-4-oxo-azetidin-1-yl]-acetic acid

Chemical Property of [(2S,3R)-2-(1,1-Dimethyl-2-phenylsulfanyl-ethyl)-3-methoxy-4-oxo-azetidin-1-yl]-acetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [(2S,3R)-2-(1,1-Dimethyl-2-phenylsulfanyl-ethyl)-3-methoxy-4-oxo-azetidin-1-yl]-acetic acid

There total 3 articles about [(2S,3R)-2-(1,1-Dimethyl-2-phenylsulfanyl-ethyl)-3-methoxy-4-oxo-azetidin-1-yl]-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

[(2R,3S)-2-(1,1-Dimethyl-2-phenylsulfanyl-ethyl)-3-methoxy-4-oxo-azetidin-1-yl]-acetic acid ethyl ester (86255-86-9) → [(2S,3R)-2-(1,1-Dimethyl-2-phenylsulfanyl-ethyl)-3-methoxy-4-oxo-azetidin-1-yl]-acetic acid (86255-87-0)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; water; Ambient temperature;

DOI:10.1016/S0040-4039(00)81349-0

Reference yield:

3-(phenylthio)-2,2-dimethylpropanal (20967-51-5) → [(2S,3R)-2-(1,1-Dimethyl-2-phenylsulfanyl-ethyl)-3-methoxy-4-oxo-azetidin-1-yl]-acetic acid (86255-87-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 90 percent / triethylamine, magnesium sulfate / CH₂Cl₂

2: 81 percent / triethylamine / CH₂Cl₂ / Ambient temperature

3: 98 percent / 0.5N NaOH / tetrahydrofuran; H₂O / Ambient temperature

With sodium hydroxide; magnesium sulfate; triethylamine; In tetrahydrofuran; dichloromethane; water;

DOI:10.1016/S0040-4039(00)81349-0

Reference yield:

[2,2-Dimethyl-3-phenylsulfanyl-prop-(Z)-ylideneamino]-acetic acid ethyl ester (86255-85-8) → [(2S,3R)-2-(1,1-Dimethyl-2-phenylsulfanyl-ethyl)-3-methoxy-4-oxo-azetidin-1-yl]-acetic acid (86255-87-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / triethylamine / CH₂Cl₂ / Ambient temperature

2: 98 percent / 0.5N NaOH / tetrahydrofuran; H₂O / Ambient temperature

With sodium hydroxide; triethylamine; In tetrahydrofuran; dichloromethane; water;

DOI:10.1016/S0040-4039(00)81349-0

upstream raw materials:

[(2R,3S)-2-(1,1-Dimethyl-2-phenylsulfanyl-ethyl)-3-methoxy-4-oxo-azetidin-1-yl]-acetic acid ethyl ester

3-(phenylthio)-2,2-dimethylpropanal

[2,2-Dimethyl-3-phenylsulfanyl-prop-(Z)-ylideneamino]-acetic acid ethyl ester

Downstream raw materials:

[(2R,3S)-2-(1,1-Dimethyl-2-phenylsulfanyl-ethyl)-3-methoxy-4-oxo-azetidin-1-yl]-acetic acid 2-trimethylsilanyl-ethyl ester

[(2R,3S)-2-(2-Chloro-1,1-dimethyl-2-phenylsulfanyl-ethyl)-3-methoxy-4-oxo-azetidin-1-yl]-acetic acid 2-trimethylsilanyl-ethyl ester

[(2R,3S)-2-(1,1-Dimethyl-2,2-bis-phenylsulfanyl-ethyl)-3-methoxy-4-oxo-azetidin-1-yl]-acetic acid 2-trimethylsilanyl-ethyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 86255-87-0 [(2S,3R)-2-(1,1-Dimethyl-2-phenylsulfanyl-ethyl)-3-methoxy-4-oxo-azetidin-1-yl]-acetic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send