(6S,9S,15S,18S)-18-(4-hydroxybenzyl)-15-isobutyl-2,2,6,9-tetramethyl-4,7,10,13,16-pentaoxo-3-oxa-5,8,11,14,17-pentaazanonadecan-19-oic acid

Base Information

• Chemical Name: (6S,9S,15S,18S)-18-(4-hydroxybenzyl)-15-isobutyl-2,2,6,9-tetramethyl-4,7,10,13,16-pentaoxo-3-oxa-5,8,11,14,17-pentaazanonadecan-19-oic acid
• CAS No.: 1620161-81-0
• Molecular Formula: C₂₈H₄₃N₅O₉
• Molecular Weight: 593.678

Synonyms:(6S,9S,15S,18S)-18-(4-hydroxybenzyl)-15-isobutyl-2,2,6,9-tetramethyl-4,7,10,13,16-pentaoxo-3-oxa-5,8,11,14,17-pentaazanonadecan-19-oic acid

Chemical Property of (6S,9S,15S,18S)-18-(4-hydroxybenzyl)-15-isobutyl-2,2,6,9-tetramethyl-4,7,10,13,16-pentaoxo-3-oxa-5,8,11,14,17-pentaazanonadecan-19-oic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (6S,9S,15S,18S)-18-(4-hydroxybenzyl)-15-isobutyl-2,2,6,9-tetramethyl-4,7,10,13,16-pentaoxo-3-oxa-5,8,11,14,17-pentaazanonadecan-19-oic acid

There total 11 articles about (6S,9S,15S,18S)-18-(4-hydroxybenzyl)-15-isobutyl-2,2,6,9-tetramethyl-4,7,10,13,16-pentaoxo-3-oxa-5,8,11,14,17-pentaazanonadecan-19-oic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

Gly-Leu-Tyr (4306-24-5) + (S)-S-(4-chlorophenyl) 2-((S)-2-((tert-butoxycarbonyl)amino)propanamido)propanethioate (1620161-71-8) → (6S,9S,15S,18S)-18-(4-hydroxybenzyl)-15-isobutyl-2,2,6,9-tetramethyl-4,7,10,13,16-pentaoxo-3-oxa-5,8,11,14,17-pentaazanonadecan-19-oic acid (1620161-81-0)

Guidance literature:

In dimethyl sulfoxide; at 20 ℃; for 25h; Inert atmosphere;

DOI:10.1021/ol501669n

Reference yield: 84.0%

Gly-Leu-Tyr (4306-24-5) + (S)-S-phenyl 2-((S)-2-((tert-butoxycarbonyl)amino)propanamido)propanethioate (1620161-69-4) → (6S,9S,15S,18S)-18-(4-hydroxybenzyl)-15-isobutyl-2,2,6,9-tetramethyl-4,7,10,13,16-pentaoxo-3-oxa-5,8,11,14,17-pentaazanonadecan-19-oic acid (1620161-81-0)

Guidance literature:

With benzotriazol-1-ol; In dimethyl sulfoxide; at 20 ℃; for 25h; Reagent/catalyst; Inert atmosphere;

DOI:10.1021/ol501669n

Reference yield: 81.0%

Gly-Leu-Tyr (4306-24-5) + (S)-S-(4-nitrophenyl) 2-((S)-2-((tert-butoxycarbonyl)amino)propanamido)propanethioate (1620161-68-3) → (6S,9S,15S,18S)-18-(4-hydroxybenzyl)-15-isobutyl-2,2,6,9-tetramethyl-4,7,10,13,16-pentaoxo-3-oxa-5,8,11,14,17-pentaazanonadecan-19-oic acid (1620161-81-0)

Guidance literature:

In dimethyl sulfoxide; at 20 ℃; for 25h; Solvent; Time; Inert atmosphere;

DOI:10.1021/ol501669n

upstream raw materials:

Gly-Leu-Tyr

(S)-S-(4-nitrophenyl) 2-((S)-2-((tert-butoxycarbonyl)amino)propanamido)propanethioate

(S)-S-phenyl 2-((S)-2-((tert-butoxycarbonyl)amino)propanamido)propanethioate

(S)-S-(4-methoxyphenyl) 2-((S)-2-((tert-butoxycarbonyl)amino)propanamido)propanethioate

Downstream raw materials:

Boc-Ala-Ala-Gly-Leu-Tyr-OSC₆H₄-4NO₂

cyclo[-Ala-Ala-Gly-Leu-Tyr-]

C₄₆H₆₆N₁₀O₁₂

C₂₉H₃₈N₆O₈S

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1620161-81-0 (6S,9S,15S,18S)-18-(4-hydroxybenzyl)-15-isobutyl-2,2,6,9-tetramethyl-4,7,10,13,16-pentaoxo-3-oxa-5,8,11,14,17-pentaazanonadecan-19-oic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send