4-Chloro-3-methoxybenzenemethanamine

Base Information

• Chemical Name: 4-Chloro-3-methoxybenzenemethanamine
• CAS No.: 247569-42-2
• Molecular Formula: C8H10ClNO
• Molecular Weight: 171.626
• Hs Code.: 2922299090
• Mol file: 247569-42-2.mol

Synonyms:4-Chloro-3-methoxybenzenemethanamine;4-Chloro-3-methoxybenzylamine;

Chemical Property of 4-Chloro-3-methoxybenzenemethanamine

Chemical Property:

• Vapor Pressure: 0.0105mmHg at 25°C
• Refractive Index: 1.549
• Boiling Point: 263.1 °C at 760 mmHg
• PKA: 8.83±0.10(Predicted)
• Flash Point: 112.9 °C
• PSA: 35.25000
• Density: 1.18 g/cm³
• LogP: 2.50760
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

(4-chloro-3-methoxyphenyl)methanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Chloro-3-methoxybenzenemethanamine

There total 32 articles about 4-Chloro-3-methoxybenzenemethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

(4-chloro-3-methoxyphenyl)methanamine hydrochloride → (4-chloro-3-methoxyphenyl)methanamine (247569-42-2)

Guidance literature:

With sodium hydrogencarbonate; In water; ethyl acetate;

Reference yield: 54.0%

2-chloro-5-(azidomethyl)anisole → (4-chloro-3-methoxyphenyl)methanamine (247569-42-2)

Guidance literature:

With triphenylphosphine; In tetrahydrofuran; water; at 20 ℃; for 48h;

Reference yield:

→ 4-aminobenzyl cyanide (10406-25-4) + (4-chloro-3-methoxyphenyl)methanamine (247569-42-2)

Guidance literature:

upstream raw materials:

2-{[4-chloro-3-(methyloxy)phenyl]methyl}-1H-isoindole-1,3(2H)-dione

N-(2-chloro-5-methoxybenzyl)phthalimide

4-chloro-3-ethoxytoluene

2-(bromomethyl)-1-chloro-4-methoxybenzene

Downstream raw materials:

2-fluoro-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide

N-(4-Chloro-3-methoxybenzyl)-2-fluoro-5-methanesulfonylbenzamide

N-Benzyl-2-[2-hydroxy-1-(hydroxymethyl)ethylamino]-5-nitrobenzamide

N-(4-chloro-3-methoxybenzyl)-2-fluoro-5-vinylbenzamide

Refernces

• 1、 -. "PYRIDINONE PYRAZOLE UREA AND PYRIMIDINONE PYRAZOLE UREA DERIVATIVES". Page/Page column 145-146. . Retrieved 2008/06/13.