N-(2-hydroxy-3,5-di-tert-butylbenzaldehyde)-1-amino-2-cyclohexaneimine

Base Information

• Chemical Name: N-(2-hydroxy-3,5-di-tert-butylbenzaldehyde)-1-amino-2-cyclohexaneimine
• CAS No.: 220044-28-0
• Molecular Formula: C₂₁H₃₄N₂O
• Molecular Weight: 330.514
• Mol file: 220044-28-0.mol

Synonyms:N-(2-hydroxy-3,5-di-tert-butylbenzaldehyde)-1-amino-2-cyclohexaneimine

Chemical Property of N-(2-hydroxy-3,5-di-tert-butylbenzaldehyde)-1-amino-2-cyclohexaneimine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(2-hydroxy-3,5-di-tert-butylbenzaldehyde)-1-amino-2-cyclohexaneimine

There total 3 articles about N-(2-hydroxy-3,5-di-tert-butylbenzaldehyde)-1-amino-2-cyclohexaneimine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

3,5-di-tert-butyl-2-hydroxybenzaldehyde (37942-07-7) + (1R,2R)-(-)-1,2-diammoniumcyclohexane mono-L-(+)-tartrate (116407-32-0,32044-22-7,39961-95-0) → N-(2-hydroxy-3,5-di-tert-butylbenzaldehyde)-1-amino-2-cyclohexaneimine (220044-28-0)

Guidance literature:

(1R,2R)-(-)-1,2-diammoniumcyclohexane mono-L-(+)-tartrate; With potassium carbonate; In ethanol; water; for 2h; Heating;

3,5-di-tert-butyl-2-hydroxybenzaldehyde; In chloroform; at 0 ℃; for 48h; Further stages.;

DOI:10.1016/j.jcat.2008.02.015

Reference yield: 90.0%

3,5-di-tert-butyl-2-hydroxybenzaldehyde (37942-07-7) + (1R,2R)-1,2-diaminocyclohexane monohydrochloride (191480-63-4) → N-(2-hydroxy-3,5-di-tert-butylbenzaldehyde)-1-amino-2-cyclohexaneimine (220044-28-0)

Guidance literature:

In methanol; ethanol; at 20 ℃; for 24h;

DOI:10.1002/ejoc.200500138

Reference yield: 60.0%

3,5-di-tert-butyl-2-hydroxybenzaldehyde (37942-07-7) + (1R,2R)-1,2-diaminocyclohexane (20439-47-8) → N-(2-hydroxy-3,5-di-tert-butylbenzaldehyde)-1-amino-2-cyclohexaneimine (220044-28-0)

Guidance literature:

In chloroform; at 0 ℃; for 48h;

DOI:10.1016/S0040-4039(01)00314-8

upstream raw materials:

3,5-di-tert-butyl-2-hydroxybenzaldehyde

(1R,2R)-1,2-diaminocyclohexane

(1R,2R)-1,2-diaminocyclohexane monohydrochloride

(1R,2R)-(-)-1,2-diammoniumcyclohexane mono-L-(+)-tartrate

Downstream raw materials:

2-({[(1R,2R)-2-aminocyclohexyl]amino}methyl)-4,6-di-tert-butylphenol

tert-butyl N-[(1R,2R)-2-{[(3,5-di-tert-butyl-2-hydroxyphenyl)methyl]amino}cyclohexyl]carbamate

2,4-di-tert-butyl-6-((E)-(((1R,2R)-2-((3,5-di-tert-butyl-2-hydroxybenzyl)(methyl)amino)cyclohexyl)imino)methyl)phenol

C₃₃H₄₇ClN₂O₂