ethyl 4-(phenylsulfonyl)benzoate

Base Information

• Chemical Name: ethyl 4-(phenylsulfonyl)benzoate
• CAS No.: 101094-06-8
• Molecular Formula: C₁₅H₁₄O₄S
• Molecular Weight: 290.34
• Mol file: 101094-06-8.mol

Synonyms:ethyl 4-(phenylsulfonyl)benzoate

Chemical Property of ethyl 4-(phenylsulfonyl)benzoate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of ethyl 4-(phenylsulfonyl)benzoate

There total 16 articles about ethyl 4-(phenylsulfonyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

Ethyl 4-bromobenzoate (5798-75-4) + sodium benzenesulfonate (873-55-2) → ethyl 4-(phenylsulfonyl)benzoate (101094-06-8)

Guidance literature:

With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; caesium carbonate; In dimethyl sulfoxide; at 20 ℃; for 24h; Inert atmosphere; Irradiation;

DOI:10.1002/chem.201905281

Reference yield: 85.0%

C9H9ClO4SZn*MgCl2*LiCl + Diphenyliodonium triflate (66003-76-7) → ethyl 4-(phenylsulfonyl)benzoate (101094-06-8)

Guidance literature:

C₉H₉ClO₄SZn*MgCl₂*LiCl; With sulfur dioxide; In dimethyl sulfoxide; at -40 - 25 ℃; for 1.5h; Inert atmosphere; Schlenk technique;

Diphenyliodonium triflate; In N,N-dimethyl-formamide; at 90 ℃; for 24h; Solvent; Inert atmosphere; Schlenk technique;

DOI:10.1021/jo5027518

Reference yield: 83.0%

4-Azidosulfonyl-benzoic acid ethyl ester + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → ethyl 4-(phenylsulfonyl)benzoate (101094-06-8)

Guidance literature:

With trifluorormethanesulfonic acid; In dichloromethane; at 25 ℃; for 3h; regiospecific reaction;

DOI:10.1021/acs.joc.8b03046

upstream raw materials:

ethanol

4-(phenylsulfonyl)benzoic acid

phenyltolylsulfone

p-toluenesulfonyl chloride

Downstream raw materials:

p-(Phenylsulphonyl) benzoic acid hydrazide

p-aminophenyl phenyl sulfone

(4-benzenesulfonyl-phenyl)-carbamic acid ethyl ester

4-benzenesulfonyl-benzoic acid amide