(3S,4S)-2,2-Dichloro-4-pentyl-3-phenyl-3-((1R,2S)-2-phenyl-cyclohexyloxy)-cyclobutanone

Base Information

Chemical Name:(3S,4S)-2,2-Dichloro-4-pentyl-3-phenyl-3-((1R,2S)-2-phenyl-cyclohexyloxy)-cyclobutanone
CAS No.:142188-47-4
Molecular Formula:C₂₇H₃₂Cl₂O₂
Molecular Weight:459.456
Hs Code.:

Synonyms:(3S,4S)-2,2-Dichloro-4-pentyl-3-phenyl-3-((1R,2S)-2-phenyl-cyclohexyloxy)-cyclobutanone

Suppliers and Price of (3S,4S)-2,2-Dichloro-4-pentyl-3-phenyl-3-((1R,2S)-2-phenyl-cyclohexyloxy)-cyclobutanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3S,4S)-2,2-Dichloro-4-pentyl-3-phenyl-3-((1R,2S)-2-phenyl-cyclohexyloxy)-cyclobutanone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3S,4S)-2,2-Dichloro-4-pentyl-3-phenyl-3-((1R,2S)-2-phenyl-cyclohexyloxy)-cyclobutanone

There total 5 articles about (3S,4S)-2,2-Dichloro-4-pentyl-3-phenyl-3-((1R,2S)-2-phenyl-cyclohexyloxy)-cyclobutanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 142188-46-3
C₂₅H₃₂O

: 76-02-8
trifluoroacetyl chloride

: 142188-47-4
(3S,4S)-2,2-Dichloro-4-pentyl-3-phenyl-3-((1R,2S)-2-phenyl-cyclohexyloxy)-cyclobutanone

Guidance literature:: With copper; zinc; In diethyl ether; at 20 ℃; for 6h;
DOI:10.1021/jo00043a003

Reference yield:

: 98919-68-7
(1R,2S)-trans-2-phenylcyclohexanol

: 142188-47-4
(3S,4S)-2,2-Dichloro-4-pentyl-3-phenyl-3-((1R,2S)-2-phenyl-cyclohexyloxy)-cyclobutanone

Guidance literature:: Multi-step reaction with 3 steps

1: 99 percent / pyridine, DMAP / 12 h / 20 °C

2: Zn, TiCl₄, TMEDA / tetrahydrofuran; CH₂Cl₂ / 3 h / 0 to 20 deg C

3: 79 percent / Zn-Cu / diethyl ether / 6 h / 20 °C

With pyridine; dmap; N,N,N,N,-tetramethylethylenediamine; titanium tetrachloride; copper; zinc; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1021/jo00043a003

Reference yield:

: 58133-26-9
1,1-dibromohexane

: 142188-47-4
(3S,4S)-2,2-Dichloro-4-pentyl-3-phenyl-3-((1R,2S)-2-phenyl-cyclohexyloxy)-cyclobutanone

Guidance literature:: Multi-step reaction with 2 steps

1: Zn, TiCl₄, TMEDA / tetrahydrofuran; CH₂Cl₂ / 3 h / 0 to 20 deg C

2: 79 percent / Zn-Cu / diethyl ether / 6 h / 20 °C

With N,N,N,N,-tetramethylethylenediamine; titanium tetrachloride; copper; zinc; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1021/jo00043a003