C₂₆H₂₆N₂O₅

Base Information

• Chemical Name: C₂₆H₂₆N₂O₅
• CAS No.: 1246617-11-7
• Molecular Formula: C₂₆H₂₆N₂O₅
• Molecular Weight: 446.503
• Mol file: 1246617-11-7.mol

Synonyms:C₂₆H₂₆N₂O₅

Chemical Property of C₂₆H₂₆N₂O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₆H₂₆N₂O₅

There total 11 articles about C₂₆H₂₆N₂O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C24H22N2O5 (1246617-10-6) + methyl iodide (74-88-4) → C26H26N2O5 (1246617-11-7)

Guidance literature:

C₂₄H₂₂N₂O₅; With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

methyl iodide; In N,N-dimethyl-formamide; at 20 ℃; for 3.5h;

Reference yield:

Methyl 4-chloroacetoacetate (32807-28-6,935731-94-5) → C26H26N2O5 (1246617-11-7)

Guidance literature:

Multi-step reaction with 6 steps

1.1: sodium tert-pentoxide / tetrahydrofuran / 2 h / 20 - 40 °C / Inert atmosphere

1.2: 2 h / 0 - 20 °C / Cooling with ice

2.1: 1,4-dioxane / 6 h / 20 °C

3.1: sodium t-butanolate / 1,3-dimethyl-2-imidazolidinone / 7 h / 20 - 30 °C / Inert atmosphere

3.2: 15 h / 20 °C

4.1: toluene / 2.5 h / 100 °C

5.1: hydrogenchloride / ethyl acetate / 0.5 h / 20 °C

6.1: caesium carbonate / N,N-dimethyl-formamide / 0.5 h / 20 °C

6.2: 3.5 h / 20 °C

With hydrogenchloride; sodium tert-pentoxide; caesium carbonate; sodium t-butanolate; In tetrahydrofuran; 1,4-dioxane; 1,3-dimethyl-2-imidazolidinone; ethyl acetate; N,N-dimethyl-formamide; toluene;

Reference yield:

benzyl alcohol (100-51-6,185532-71-2) → C26H26N2O5 (1246617-11-7)

Guidance literature:

Multi-step reaction with 6 steps

1.1: sodium tert-pentoxide / tetrahydrofuran / 2 h / 20 - 40 °C / Inert atmosphere

1.2: 2 h / 0 - 20 °C / Cooling with ice

2.1: 1,4-dioxane / 6 h / 20 °C

3.1: sodium t-butanolate / 1,3-dimethyl-2-imidazolidinone / 7 h / 20 - 30 °C / Inert atmosphere

3.2: 15 h / 20 °C

4.1: toluene / 2.5 h / 100 °C

5.1: hydrogenchloride / ethyl acetate / 0.5 h / 20 °C

6.1: caesium carbonate / N,N-dimethyl-formamide / 0.5 h / 20 °C

6.2: 3.5 h / 20 °C

With hydrogenchloride; sodium tert-pentoxide; caesium carbonate; sodium t-butanolate; In tetrahydrofuran; 1,4-dioxane; 1,3-dimethyl-2-imidazolidinone; ethyl acetate; N,N-dimethyl-formamide; toluene;

upstream raw materials:

C₂₄H₂₂N₂O₅

methyl iodide

Methyl 4-chloroacetoacetate

benzyl alcohol

Downstream raw materials:

C₂₅H₂₄N₂O₅

C₁₈H₁₈N₂O₅