(4-methoxyphenyl)methyl hex-5-enoate

Base Information

• Chemical Name: (4-methoxyphenyl)methyl hex-5-enoate
• CAS No.: 187851-95-2
• Molecular Formula: C₁₄H₁₈O₃
• Molecular Weight: 234.295
• Mol file: 187851-95-2.mol

Synonyms:(4-methoxyphenyl)methyl hex-5-enoate

Chemical Property of (4-methoxyphenyl)methyl hex-5-enoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4-methoxyphenyl)methyl hex-5-enoate

There total 1 articles about (4-methoxyphenyl)methyl hex-5-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

5-hexenoic acid (1577-22-6) + p-methoxybenzyl chloride (824-94-2) → (4-methoxyphenyl)methyl hex-5-enoate (187851-95-2)

Guidance literature:

With sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 45 ℃; for 72h;

DOI:10.1021/jo962166h

Reference yield: 59.0%

(4-methoxyphenyl)methyl hex-5-enoate (187851-95-2) → (4-methoxyphenyl)methyl (R)-5,6-dihydroxyhexanoate (187851-96-3) + (S)-5,6-Dihydroxy-hexanoic acid 4-methoxy-benzyl ester (213532-96-8)

Guidance literature:

With potassium osmate(VI); 1,4-bis(dihydroquinidinyl)anthraquinone; water; sodium hydrogencarbonate; potassium carbonate; potassium hexacyanoferrate(III); In tert-butyl alcohol; at 0 ℃; for 12h; Yields of byproduct given;

DOI:10.1055/s-1998-2123

Reference yield: 51.0%

(4-methoxyphenyl)methyl hex-5-enoate (187851-95-2) → (4-methoxyphenyl)methyl (R)-5,6-dihydroxyhexanoate (187851-96-3)

Guidance literature:

With (DHQD)2AQN; K₂OsO₂(OH)2; sodium hydrogencarbonate; potassium carbonate; potassium hexacyanoferrate(III); In tert-butyl alcohol; at 0 ℃; for 48h;

DOI:10.1021/jo962166h

upstream raw materials:

5-hexenoic acid

p-methoxybenzyl chloride

Downstream raw materials:

(4-methoxyphenyl)methyl (R)-5,6-dihydroxyhexanoate

(S)-5,6-Dihydroxy-hexanoic acid 4-methoxy-benzyl ester

(+)-(S)-6-hydroxymethyl-2-piperidinone

(S)-6-((tert-butyldiphenylsilyloxy)methyl)piperidin-2-one