5-chloro-7-[4-(tetrahydro-pyran-4-yloxy)-3-trifluoromethyl-phenyl]-[1,6]naphthyridine

Base Information

Chemical Name:5-chloro-7-[4-(tetrahydro-pyran-4-yloxy)-3-trifluoromethyl-phenyl]-[1,6]naphthyridine
CAS No.:1319737-54-6
Molecular Formula:C₂₀H₁₆ClF₃N₂O₂
Molecular Weight:408.807
Hs Code.:

Synonyms:5-chloro-7-[4-(tetrahydro-pyran-4-yloxy)-3-trifluoromethyl-phenyl]-[1,6]naphthyridine

Suppliers and Price of 5-chloro-7-[4-(tetrahydro-pyran-4-yloxy)-3-trifluoromethyl-phenyl]-[1,6]naphthyridine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-chloro-7-[4-(tetrahydro-pyran-4-yloxy)-3-trifluoromethyl-phenyl]-[1,6]naphthyridine

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Technology Process of 5-chloro-7-[4-(tetrahydro-pyran-4-yloxy)-3-trifluoromethyl-phenyl]-[1,6]naphthyridine

There total 1 articles about 5-chloro-7-[4-(tetrahydro-pyran-4-yloxy)-3-trifluoromethyl-phenyl]-[1,6]naphthyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1319737-54-6
5-chloro-7-[4-(tetrahydro-pyran-4-yloxy)-3-trifluoromethyl-phenyl]-[1,6]naphthyridine

Guidance literature:

Reference yield: 27.0%

: 1165450-70-3
(R)-4-(hydroxymethyl)pyrrolidine-2-one

: 1319737-54-6
5-chloro-7-[4-(tetrahydro-pyran-4-yloxy)-3-trifluoromethyl-phenyl]-[1,6]naphthyridine

: 1319737-93-3
(R)-4-{7-[4-(tetrahydro-pyran-4-yloxy)-3-trifluoromethyl-phenyl]-[1,6]naphthyridine-5-yloxymethyl}pyrrolidine-2-one

Guidance literature:: (R)-4-(hydroxymethyl)pyrrolidine-2-one; With sodium hydride; In N,N-dimethyl acetamide; mineral oil; at 20 ℃; for 0.166667h; Inert atmosphere;

5-chloro-7-[4-(tetrahydro-pyran-4-yloxy)-3-trifluoromethyl-phenyl]-[1,6]naphthyridine; In N,N-dimethyl acetamide; at 70 ℃; Inert atmosphere;