carbonic acid 8-(2,6-diethyl-4-methylphenyl)-3-methoxy-9-oxo-2,3,4,5-tetrahydro-1H,9H-pyrazolo[1,2-a][1,2,5]triazepin-7-yl ester ethyl ester

Base Information

Chemical Name:carbonic acid 8-(2,6-diethyl-4-methylphenyl)-3-methoxy-9-oxo-2,3,4,5-tetrahydro-1H,9H-pyrazolo[1,2-a][1,2,5]triazepin-7-yl ester ethyl ester
CAS No.:1416807-99-2
Molecular Formula:C₂₂H₃₁N₃O₅
Molecular Weight:417.505
Hs Code.:

Synonyms:carbonic acid 8-(2,6-diethyl-4-methylphenyl)-3-methoxy-9-oxo-2,3,4,5-tetrahydro-1H,9H-pyrazolo[1,2-a][1,2,5]triazepin-7-yl ester ethyl ester

Suppliers and Price of carbonic acid 8-(2,6-diethyl-4-methylphenyl)-3-methoxy-9-oxo-2,3,4,5-tetrahydro-1H,9H-pyrazolo[1,2-a][1,2,5]triazepin-7-yl ester ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of carbonic acid 8-(2,6-diethyl-4-methylphenyl)-3-methoxy-9-oxo-2,3,4,5-tetrahydro-1H,9H-pyrazolo[1,2-a][1,2,5]triazepin-7-yl ester ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of carbonic acid 8-(2,6-diethyl-4-methylphenyl)-3-methoxy-9-oxo-2,3,4,5-tetrahydro-1H,9H-pyrazolo[1,2-a][1,2,5]triazepin-7-yl ester ethyl ester

There total 4 articles about carbonic acid 8-(2,6-diethyl-4-methylphenyl)-3-methoxy-9-oxo-2,3,4,5-tetrahydro-1H,9H-pyrazolo[1,2-a][1,2,5]triazepin-7-yl ester ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 1416807-67-4
8-(2,6-diethyl-4-methylphenyl)-3-methoxytetrahydropyrazolo[1,2-a][1,2,5]triazepine-7,9-dione

: 541-41-3
chloroformic acid ethyl ester

: 1416807-99-2
carbonic acid 8-(2,6-diethyl-4-methylphenyl)-3-methoxy-9-oxo-2,3,4,5-tetrahydro-1H,9H-pyrazolo[1,2-a][1,2,5]triazepin-7-yl ester ethyl ester

Guidance literature:: With dmap; triethylamine; In tetrahydrofuran; at 0 - 10 ℃; for 1h; Inert atmosphere;
DOI:10.1016/j.bmcl.2017.12.042

Reference yield:

: 1416808-55-3
C₂₁H₃₃N₃O₄

: 1416807-99-2
carbonic acid 8-(2,6-diethyl-4-methylphenyl)-3-methoxy-9-oxo-2,3,4,5-tetrahydro-1H,9H-pyrazolo[1,2-a][1,2,5]triazepin-7-yl ester ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: sodium methylate / N,N-dimethyl-formamide / 10 °C / Inert atmosphere; Heating

2: triethylamine; dmap / tetrahydrofuran / 1 h / 0 - 10 °C / Inert atmosphere

With dmap; sodium methylate; triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2017.12.042

Reference yield:

: 886230-70-2
(2,6-diethyl-4-methylphenyl)acetic acid chloride

: 1416807-99-2
carbonic acid 8-(2,6-diethyl-4-methylphenyl)-3-methoxy-9-oxo-2,3,4,5-tetrahydro-1H,9H-pyrazolo[1,2-a][1,2,5]triazepin-7-yl ester ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine; dmap / tetrahydrofuran / 5 h / 0 - 20 °C / Inert atmosphere

2: sodium methylate / N,N-dimethyl-formamide / 10 °C / Inert atmosphere; Heating

3: triethylamine; dmap / tetrahydrofuran / 1 h / 0 - 10 °C / Inert atmosphere

With dmap; sodium methylate; triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2017.12.042