(S)-4-((S)-Methoxy-phenyl-methyl)-2,2-dimethyl-[1,3]dioxolane

Base Information

• Chemical Name: (S)-4-((S)-Methoxy-phenyl-methyl)-2,2-dimethyl-[1,3]dioxolane
• CAS No.: 170164-71-3
• Molecular Formula: C₁₃H₁₈O₃
• Molecular Weight: 222.284
• Mol file: 170164-71-3.mol

Synonyms:(S)-4-((S)-Methoxy-phenyl-methyl)-2,2-dimethyl-[1,3]dioxolane

Chemical Property of (S)-4-((S)-Methoxy-phenyl-methyl)-2,2-dimethyl-[1,3]dioxolane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-4-((S)-Methoxy-phenyl-methyl)-2,2-dimethyl-[1,3]dioxolane

There total 1 articles about (S)-4-((S)-Methoxy-phenyl-methyl)-2,2-dimethyl-[1,3]dioxolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(S)-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-phenyl-methanol + methyl iodide (74-88-4) → (S)-4-((S)-Methoxy-phenyl-methyl)-2,2-dimethyl-[1,3]dioxolane (170164-71-3)

Guidance literature:

With sodium hydride; In tetrahydrofuran;

DOI:10.1080/00397919508011831

Reference yield: 100.0%

(S)-4-((S)-Methoxy-phenyl-methyl)-2,2-dimethyl-[1,3]dioxolane (170164-71-3) → (2S,3S)-3-Methoxy-3-phenyl-propane-1,2-diol

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; for 4.5h;

DOI:10.1080/00397919508011831

Reference yield:

(S)-4-((S)-Methoxy-phenyl-methyl)-2,2-dimethyl-[1,3]dioxolane (170164-71-3) → (S)-2-methoxy-2-phenylacetic acid (26164-26-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / 1N aq. HCl / tetrahydrofuran / 4.5 h

2: 91 percent / RuO₄*H₂O, NaIO₄ / CCl₄; acetonitrile; H₂O / 0.67 h

With hydrogenchloride; sodium periodate; ruthenium tetroxide; In tetrahydrofuran; tetrachloromethane; water; acetonitrile;

DOI:10.1080/00397919508011831

upstream raw materials:

methyl iodide

Downstream raw materials:

(S)-2-methoxy-2-phenylacetic acid