C₅₂H₅₀O₄

Base Information

• Chemical Name: C₅₂H₅₀O₄
• CAS No.: 1427498-02-9
• Molecular Formula: C₅₂H₅₀O₄
• Molecular Weight: 738.967
• Mol file: 1427498-02-9.mol

Synonyms:C₅₂H₅₀O₄

Chemical Property of C₅₂H₅₀O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₂H₅₀O₄

There total 3 articles about C₅₂H₅₀O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

4-tert-Butylphenylacetylene (772-38-3) + 1,4-diiodo-(E)-2,5-bis(4-(1,3-dioxolan-2-yl)styryl)benzene → C52H50O4 (1427498-02-9)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In tetrahydrofuran; for 72h; Inert atmosphere; Heating;

DOI:10.1021/jo302456n

Reference yield:

[2,5-dichloro-4-(diethoxyphosphorylmethyl)benzyl]phosphonic acid diethyl ester (660870-76-8) → C52H50O4 (1427498-02-9)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium tert-butylate / tetrahydrofuran / 2 h / 0 - 22 °C / Inert atmosphere

2: triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / tetrahydrofuran / 72 h / Inert atmosphere; Heating

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; potassium tert-butylate; triethylamine; In tetrahydrofuran;

DOI:10.1021/jo302456n

Reference yield:

4-(1,3-dioxolan-2-yl)benzaldehyde (40681-88-7) → C52H50O4 (1427498-02-9)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium tert-butylate / tetrahydrofuran / 2 h / 0 - 22 °C / Inert atmosphere

2: triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / tetrahydrofuran / 72 h / Inert atmosphere; Heating

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; potassium tert-butylate; triethylamine; In tetrahydrofuran;

DOI:10.1021/jo302456n

upstream raw materials:

[2,5-dichloro-4-(diethoxyphosphorylmethyl)benzyl]phosphonic acid diethyl ester

4-(1,3-dioxolan-2-yl)benzaldehyde

4-tert-Butylphenylacetylene

Downstream raw materials:

1,4-bis(4-tert-butylphenylethynyl)-(E)-2,5-bis(4-(((2-hydroxyethyl)imino)methyl)styryl)benzene

1,4-bis(4-tert-butylphenylethynyl)-(E)-2,5-bis(4-(((pyridin-2-ylmethyl)imino)methyl)styryl)benzene

1,4-bis(4-tert-butylphenylethynyl)-(E)-2,5-bis(4-formylstyryl)benzene

1,4-bis(4-tert-butylphenylethynyl)-(E)-2,5-bis(4-((cyclopropylimino)methyl)styryl)benzene