2-(4-methoxyphenyl)-3-methyl-5-(trifluoromethyl)quinoxaline

Base Information

• Chemical Name: 2-(4-methoxyphenyl)-3-methyl-5-(trifluoromethyl)quinoxaline
• CAS No.: 1221265-50-4
• Molecular Formula: C₁₇H₁₃F₃N₂O
• Molecular Weight: 318.298
• Mol file: 1221265-50-4.mol

Synonyms:2-(4-methoxyphenyl)-3-methyl-5-(trifluoromethyl)quinoxaline

Chemical Property of 2-(4-methoxyphenyl)-3-methyl-5-(trifluoromethyl)quinoxaline

Chemical Property:

Purity/Quality:

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Technology Process of 2-(4-methoxyphenyl)-3-methyl-5-(trifluoromethyl)quinoxaline

There total 1 articles about 2-(4-methoxyphenyl)-3-methyl-5-(trifluoromethyl)quinoxaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(4-methoxy-phenyl)-propane-1,2-dione (10557-27-4) + 3-(trifluoromethyl)benzene-1,2-diamine (360-60-1) → 2-(4-methoxyphenyl)-3-methyl-5-(trifluoromethyl)quinoxaline (1221265-50-4) + 3-(4-methoxyphenyl)-2-methyl-5-(trifluoromethyl)quinoxaline (1221265-51-5)

Guidance literature:

In ethanol; at 20 ℃; for 1h;

Reference yield: 90.0%

2-(4-methoxyphenyl)-3-methyl-5-(trifluoromethyl)quinoxaline (1221265-50-4) → 4-[3-methyl-5-(trifluoromethyl)-quinoxalin-2-yl]phenol (1221265-52-6)

Guidance literature:

With water; hydrogen bromide; acetic acid; at 90 ℃; Reflux;

upstream raw materials:

1-(4-methoxy-phenyl)-propane-1,2-dione

3-(trifluoromethyl)benzene-1,2-diamine

Downstream raw materials:

4-[3-methyl-5-(trifluoromethyl)-quinoxalin-2-yl]phenol