2-(1-(3,5-bis(trifluoromethyl)benzyl)-3-isopropyl-2-oxopyrrolidin-3-yl)acetaldehyde

Base Information

Chemical Name:2-(1-(3,5-bis(trifluoromethyl)benzyl)-3-isopropyl-2-oxopyrrolidin-3-yl)acetaldehyde
CAS No.:1328884-93-0
Molecular Formula:C₁₈H₁₉F₆NO₂
Molecular Weight:395.345
Hs Code.:

Synonyms:2-(1-(3,5-bis(trifluoromethyl)benzyl)-3-isopropyl-2-oxopyrrolidin-3-yl)acetaldehyde

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Chemical Property of 2-(1-(3,5-bis(trifluoromethyl)benzyl)-3-isopropyl-2-oxopyrrolidin-3-yl)acetaldehyde

Chemical Property:

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Technology Process of 2-(1-(3,5-bis(trifluoromethyl)benzyl)-3-isopropyl-2-oxopyrrolidin-3-yl)acetaldehyde

There total 7 articles about 2-(1-(3,5-bis(trifluoromethyl)benzyl)-3-isopropyl-2-oxopyrrolidin-3-yl)acetaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1328884-88-3
3-allyl-1-(3,5-bis(trifluoromethyl)benzyl)-3-isopropylpyrrolidin-2-one

: 1328884-93-0
2-(1-(3,5-bis(trifluoromethyl)benzyl)-3-isopropyl-2-oxopyrrolidin-3-yl)acetaldehyde

Guidance literature:: With ozone; In acetone; at -78 ℃; Inert atmosphere;

Reference yield:

: 1328884-90-7
C₁₁H₁₆O₃

: 1328884-93-0
2-(1-(3,5-bis(trifluoromethyl)benzyl)-3-isopropyl-2-oxopyrrolidin-3-yl)acetaldehyde

Guidance literature:: Multi-step reaction with 4 steps

1: sodium tetrahydroborate / methanol / 0 - 20 °C

2: lithium hydroxide; methanol / water; tetrahydrofuran / 4 h / 20 °C

3: hydrogen / Lindlar catalyst / methanol / 2 h

4: ozone / acetone / -78 °C / Inert atmosphere

With methanol; sodium tetrahydroborate; hydrogen; ozone; lithium hydroxide; Lindlar catalyst; In tetrahydrofuran; methanol; water; acetone;

Reference yield:

: 1328884-89-4
C₁₂H₁₈O₂

: 1328884-93-0
2-(1-(3,5-bis(trifluoromethyl)benzyl)-3-isopropyl-2-oxopyrrolidin-3-yl)acetaldehyde

Guidance literature:: Multi-step reaction with 5 steps

1: triphenylphosphine; ozone / dichloromethane / -78 - 20 °C

2: sodium tetrahydroborate / methanol / 0 - 20 °C

3: lithium hydroxide; methanol / water; tetrahydrofuran / 4 h / 20 °C

4: hydrogen / Lindlar catalyst / methanol / 2 h

5: ozone / acetone / -78 °C / Inert atmosphere

With methanol; sodium tetrahydroborate; hydrogen; ozone; triphenylphosphine; lithium hydroxide; Lindlar catalyst; In tetrahydrofuran; methanol; dichloromethane; water; acetone;