(+)-(1R,2S,3R)-3-[N-phenylsulfonyl-N-(3,5-dimethylphenyl)amino]-2-bornanyl 2-(trifluoromethyl)acrylate

Base Information

• Chemical Name: (+)-(1R,2S,3R)-3-[N-phenylsulfonyl-N-(3,5-dimethylphenyl)amino]-2-bornanyl 2-(trifluoromethyl)acrylate
• CAS No.: 653595-54-1
• Molecular Formula: C₂₈H₃₂F₃NO₄S
• Molecular Weight: 535.628

Synonyms:(+)-(1R,2S,3R)-3-[N-phenylsulfonyl-N-(3,5-dimethylphenyl)amino]-2-bornanyl 2-(trifluoromethyl)acrylate

Chemical Property of (+)-(1R,2S,3R)-3-[N-phenylsulfonyl-N-(3,5-dimethylphenyl)amino]-2-bornanyl 2-(trifluoromethyl)acrylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+)-(1R,2S,3R)-3-[N-phenylsulfonyl-N-(3,5-dimethylphenyl)amino]-2-bornanyl 2-(trifluoromethyl)acrylate

There total 1 articles about (+)-(1R,2S,3R)-3-[N-phenylsulfonyl-N-(3,5-dimethylphenyl)amino]-2-bornanyl 2-(trifluoromethyl)acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(trifluoromethyl)acrylic chloride (90715-73-4) + (1R,2S,3R)-3-[N-Phenylsulfonyl-N-(3,5-dimethylphenyl)amino]bornan-2-ol (87420-26-6) → (+)-(1R,2S,3R)-3-[N-phenylsulfonyl-N-(3,5-dimethylphenyl)amino]-2-bornanyl 2-(trifluoromethyl)acrylate (653595-54-1)

Guidance literature:

With pyridine;

DOI:10.1021/ol0361554

Reference yield: 81.0%

ethyl N-{[(4-nitrobenzene)sulfonyl]oxy}carbamate (2955-74-0) + (+)-(1R,2S,3R)-3-[N-phenylsulfonyl-N-(3,5-dimethylphenyl)amino]-2-bornanyl 2-(trifluoromethyl)acrylate (653595-54-1) → (1R,2S,3R)-3-[N-phenylsulfonyl-N-(3,5-dimethylphenyl)amino]-2-bornanyl N-(ethoxycarbonyl)-N-[(4-nitrophenylsulfonyl)oxy]-2-aminomethyl-3,3,3-trifluoropropanoate (653595-66-5)

Guidance literature:

With calcium oxide; In dichloromethane; at 25 ℃; for 3h;

DOI:10.1021/ol0361554

Reference yield: 72.0%

ethyl N-{[(4-nitrobenzene)sulfonyl]oxy}carbamate (2955-74-0) + (+)-(1R,2S,3R)-3-[N-phenylsulfonyl-N-(3,5-dimethylphenyl)amino]-2-bornanyl 2-(trifluoromethyl)acrylate (653595-54-1) → (+)-1-ethyl 2-(1R,2S,3R)-3-[N-phenylsulfonyl-N-(3,5-dimethylphenyl)amino]-2-bornanyl 2-(trifluoromethyl)aziridine-1,2-dicarboxylate

Guidance literature:

With sodium hydride; In tetrahydrofuran; at -78 ℃; for 12h;

DOI:10.1021/ol0361554

upstream raw materials:

2-(trifluoromethyl)acrylic chloride

(1R,2S,3R)-3-[N-Phenylsulfonyl-N-(3,5-dimethylphenyl)amino]bornan-2-ol

Downstream raw materials:

(1R,2S,3R)-3-[N-phenylsulfonyl-N-(3,5-dimethylphenyl)amino]-2-bornanyl N-(ethoxycarbonyl)-N-[(4-nitrophenylsulfonyl)oxy]-2-aminomethyl-3,3,3-trifluoropropanoate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 653595-54-1 (+)-(1R,2S,3R)-3-[N-phenylsulfonyl-N-(3,5-dimethylphenyl)amino]-2-bornanyl 2-(trifluoromethyl)acrylate

Send

Send

Metric Ton KG G Pound L ML

Send

Send