2-deoxy-1-O-dibenzylphosphoryl-2-fluoro-3,4,6,7-tetra-O-pivaloyl-L-glycero-β-D-gluco-heptopyranose

Base Information

• Chemical Name: 2-deoxy-1-O-dibenzylphosphoryl-2-fluoro-3,4,6,7-tetra-O-pivaloyl-L-glycero-β-D-gluco-heptopyranose
• CAS No.: 888487-32-9
• Molecular Formula: C₄₁H₅₈FO₁₃P
• Molecular Weight: 808.876

Synonyms:2-deoxy-1-O-dibenzylphosphoryl-2-fluoro-3,4,6,7-tetra-O-pivaloyl-L-glycero-β-D-gluco-heptopyranose

Chemical Property of 2-deoxy-1-O-dibenzylphosphoryl-2-fluoro-3,4,6,7-tetra-O-pivaloyl-L-glycero-β-D-gluco-heptopyranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-deoxy-1-O-dibenzylphosphoryl-2-fluoro-3,4,6,7-tetra-O-pivaloyl-L-glycero-β-D-gluco-heptopyranose

There total 3 articles about 2-deoxy-1-O-dibenzylphosphoryl-2-fluoro-3,4,6,7-tetra-O-pivaloyl-L-glycero-β-D-gluco-heptopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

1,5-anhydro-2-deoxy-3,4,6,7-tetra-O-pivaloyl-L-galacto-hept-1-enitol (888487-31-8) + sodium dibenzyl phosphate (97174-13-5) → 2-deoxy-1-O-dibenzylphosphoryl-2-fluoro-3,4,6,7-tetra-O-pivaloyl-L-glycero-β-D-gluco-heptopyranose (888487-32-9)

Guidance literature:

1,5-anhydro-2-deoxy-3,4,6,7-tetra-O-pivaloyl-L-galacto-hept-1-enitol; With 1-chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(trifluoromethanesulfonate); In nitromethane; at 0 - 20 ℃; for 12h; Molecular sieve;

sodium dibenzyl phosphate; With 15-crown-5; In nitromethane; at 60 ℃; for 2h;

Reference yield:

2CF3O3S(1-)*C34H58ClFN2O9(2+) + sodium dibenzyl phosphate (97174-13-5) → 2-deoxy-1-O-dibenzylphosphoryl-2-fluoro-3,4,6,7-tetra-O-pivaloyl-L-glycero-β-D-gluco-heptopyranose (888487-32-9) + C41H58FO13P

Guidance literature:

With 15-crown-5; at 20 - 60 ℃; optical yield given as %de; diastereoselective reaction; Inert atmosphere;

DOI:10.1002/chem.200801279

Reference yield:

1,5-anhydro-2-deoxy-3,4,6,7-tetra-O-pivaloyl-L-galacto-hept-1-enitol (888487-31-8) + sodium dibenzyl phosphate (97174-13-5) → 2-deoxy-1-O-dibenzylphosphoryl-2-fluoro-3,4,6,7-tetra-O-pivaloyl-L-glycero-β-D-gluco-heptopyranose (888487-32-9) + C41H58FO13P

Guidance literature:

With 15-crown-5; nitromethane; at 60 ℃; for 2h; Overall yield = 53%;

DOI:10.1002/ijch.201400148

upstream raw materials:

sodium dibenzyl phosphate

1,5-anhydro-2-deoxy-3,4,6,7-tetra-O-pivaloyl-L-galacto-hept-1-enitol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 888487-32-9 2-deoxy-1-O-dibenzylphosphoryl-2-fluoro-3,4,6,7-tetra-O-pivaloyl-L-glycero-β-D-gluco-heptopyranose

Send

Send

Metric Ton KG G Pound L ML

Send

Send