PHOSPHORIC ACID DIBENZYL ESTER, SODIUM-SALT

Base Information

• Chemical Name: PHOSPHORIC ACID DIBENZYL ESTER, SODIUM-SALT
• CAS No.: 97174-13-5
• Molecular Formula: C14H15 O4 P . Na
• Molecular Weight: 300.226
• Mol file: 97174-13-5.mol

Synonyms:Benzylsodium phosphate (6CI,7CI); Phosphoric acid, bis(phenylmethyl) ester, sodiumsalt (9CI); Sodium dibenzyl phosphate

Chemical Property of PHOSPHORIC ACID DIBENZYL ESTER, SODIUM-SALT

Chemical Property:

• PSA: 68.40000
• LogP: 3.95860

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of PHOSPHORIC ACID DIBENZYL ESTER, SODIUM-SALT

There total 1 articles about PHOSPHORIC ACID DIBENZYL ESTER, SODIUM-SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dibenzyl (methoxycarbonyl)phosphonate (59682-38-1) → Dibenzyl phosphite (17176-77-1) + sodium benzyl phosphite + sodium dibenzyl phosphate (97174-13-5) + sodium benzyl (methoxycarbonyl)phosphonate (55920-93-9) + sodium benzyl (benzyloxycarbonyl)phosphonate (137095-81-9) + benzyl alcohol (100-51-6,185532-71-2)

Guidance literature:

With water; In acetonitrile; at 36.4 ℃; for 24h; Rate constant; Mechanism; phosphate buffer pH 7.4; also with H₂⁽¹⁸⁾O;

Reference yield: 66.0%

2BF4(1-)*C31H66ClFN2O4Si3(2+) + sodium dibenzyl phosphate (97174-13-5) → dibenzyl (2-deoxy-2-fluoro-3,4,6-tri-O-tert-butyldimethylsilyl-β-D-gluco-pyranosyl)phosphate (1101183-44-1)

Guidance literature:

With 15-crown-5; at 20 - 45 ℃; diastereoselective reaction; Inert atmosphere;

DOI:10.1002/chem.200801279

Reference yield: 58.0%

1,5-anhydro-2-deoxy-3,4,6,7-tetra-O-pivaloyl-L-galacto-hept-1-enitol (888487-31-8) + sodium dibenzyl phosphate (97174-13-5) → 2-deoxy-1-O-dibenzylphosphoryl-2-fluoro-3,4,6,7-tetra-O-pivaloyl-L-glycero-β-D-gluco-heptopyranose (888487-32-9)

Guidance literature:

1,5-anhydro-2-deoxy-3,4,6,7-tetra-O-pivaloyl-L-galacto-hept-1-enitol; With 1-chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(trifluoromethanesulfonate); In nitromethane; at 0 - 20 ℃; for 12h; Molecular sieve;

sodium dibenzyl phosphate; With 15-crown-5; In nitromethane; at 60 ℃; for 2h;

upstream raw materials:

dibenzyl (methoxycarbonyl)phosphonate

Downstream raw materials:

phosphoric acid dibenzyl ester 3-benzyl-2,5-dioxo-4,4-diphenyl-imidazolidin-1-ylmethyl ester

1-Pentynyl dibenzyl phosphate

tert-Butylethynyl dibenzyl phosphate

2-deoxy-1-O-dibenzylphosphoryl-2-fluoro-3,4,6,7-tetra-O-tert-butyldimethylsilyl-L-glycero-β-D-gluco-heptopyranose