3,9-diaza-bicyclo[3.3.1]nonane-3-carboxylic acid 3,4-dichloro-phenyl ester hydrochloric acid salt

Base Information

Chemical Name:3,9-diaza-bicyclo[3.3.1]nonane-3-carboxylic acid 3,4-dichloro-phenyl ester hydrochloric acid salt
CAS No.:1186532-44-4
Molecular Formula:C₁₄H₁₆Cl₂N₂O₂*ClH
Molecular Weight:351.66
Hs Code.:

Synonyms:3,9-diaza-bicyclo[3.3.1]nonane-3-carboxylic acid 3,4-dichloro-phenyl ester hydrochloric acid salt

Suppliers and Price of 3,9-diaza-bicyclo[3.3.1]nonane-3-carboxylic acid 3,4-dichloro-phenyl ester hydrochloric acid salt

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3,9-diaza-bicyclo[3.3.1]nonane-3-carboxylic acid 3,4-dichloro-phenyl ester hydrochloric acid salt

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3,9-diaza-bicyclo[3.3.1]nonane-3-carboxylic acid 3,4-dichloro-phenyl ester hydrochloric acid salt

There total 7 articles about 3,9-diaza-bicyclo[3.3.1]nonane-3-carboxylic acid 3,4-dichloro-phenyl ester hydrochloric acid salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

: 1186532-36-4
9-methyl-3,9-diaza-bicyclo[3.3.1]nonane-3-carboxylic acid 3,4-dichloro-phenyl ester

: 1186532-44-4
3,9-diaza-bicyclo[3.3.1]nonane-3-carboxylic acid 3,4-dichloro-phenyl ester hydrochloric acid salt

Guidance literature:: 9-methyl-3,9-diaza-bicyclo[3.3.1]nonane-3-carboxylic acid 3,4-dichloro-phenyl ester; With 2,2,2-Trichloroethyl chloroformate; In toluene; for 15h; Reflux;

With acetic acid; zinc; In water; at 20 ℃; for 30h;

With hydrogenchloride; In diethyl ether;

Reference yield:

: 3431-05-8
3-benzyl-9-methyl-3,9-diaza-bicyclo[3.3.1]nonane

: 1186532-44-4
3,9-diaza-bicyclo[3.3.1]nonane-3-carboxylic acid 3,4-dichloro-phenyl ester hydrochloric acid salt

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydrogen / palladium 10% on activated carbon / ethanol / 16 h / 100 °C / 45004.5 Torr

2.1: 1,2-dimethoxyethane / 15 h / 20 °C

3.1: 2,2,2-Trichloroethyl chloroformate / toluene / 15 h / Reflux

3.2: 30 h / 20 °C

With hydrogen; 2,2,2-Trichloroethyl chloroformate; palladium 10% on activated carbon; In 1,2-dimethoxyethane; ethanol; toluene;

Reference yield:

: 182949-96-8
diethyl cis-1-methylpiperidine-2,6-dicarboxylate

: 1186532-44-4
3,9-diaza-bicyclo[3.3.1]nonane-3-carboxylic acid 3,4-dichloro-phenyl ester hydrochloric acid salt

Guidance literature:: Multi-step reaction with 5 steps

1.1: xylene / 205 °C / Reflux; Inert atmosphere

2.1: lithium aluminium tetrahydride / 1,4-dioxane / 18 h / Reflux

2.2: 80 °C

3.1: hydrogen / palladium 10% on activated carbon / ethanol / 16 h / 100 °C / 45004.5 Torr

4.1: 1,2-dimethoxyethane / 15 h / 20 °C

5.1: 2,2,2-Trichloroethyl chloroformate / toluene / 15 h / Reflux

5.2: 30 h / 20 °C

With lithium aluminium tetrahydride; hydrogen; 2,2,2-Trichloroethyl chloroformate; palladium 10% on activated carbon; In 1,4-dioxane; 1,2-dimethoxyethane; ethanol; toluene; xylene;