C₁₆H₁₉IO₄

Base Information

• Chemical Name: C₁₆H₁₉IO₄
• CAS No.: 1454769-84-6
• Molecular Formula: C₁₆H₁₉IO₄
• Molecular Weight: 402.229
• Mol file: 1454769-84-6.mol

Synonyms:C₁₆H₁₉IO₄

Chemical Property of C₁₆H₁₉IO₄

Chemical Property:

Purity/Quality:

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Technology Process of C₁₆H₁₉IO₄

There total 1 articles about C₁₆H₁₉IO₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

2-methyl-1-buten-4-ol (763-32-6) + 2-[(2-iodophenyl)methyl]propanedioic acid 1,3-dimethyl ester (122950-98-5) → C16H19IO4 (1454769-84-6)

Guidance literature:

2-[(2-iodophenyl)methyl]propanedioic acid 1,3-dimethyl ester; With sodium hydride; In tetrahydrofuran; mineral oil; at 20 ℃; for 0.5h; Inert atmosphere;

2-methyl-1-buten-4-ol; In tetrahydrofuran; mineral oil; at 20 - 40 ℃; for 3h; Inert atmosphere;

DOI:10.1021/ol402210a

Reference yield: 68.0%

N'-(4-methoxybenzylidene)-4-methylbenzenesulfonohydrazide (19350-72-2) + C16H19IO4 (1454769-84-6) → (E)-1-(4-methoxystyryl)-1-methyl-3,3-di(methoxycarbonyl)-1,2,3,4-tetrahydronaphthalene (1454770-08-1)

Guidance literature:

With palladium diacetate; triphenylphosphine; lithium tert-butoxide; In acetonitrile; at 80 ℃; for 0.5h; Inert atmosphere;

DOI:10.1021/ol402210a

Reference yield: 68.0%

C16H19IO4 (1454769-84-6) + phenyl triisopropylsilyl sulfide (156098-13-4) → dimethyl 4-methyl-4-phenylthiomethyl-3,4-dihydronaphthalene-2,2(1H)-dicarboxylate

Guidance literature:

With C₂₇H₃₆N₂*C₃H₅^(1-)*Pd⁽²⁺⁾*Cl^(1-); caesium carbonate; In toluene; at 100 ℃; for 36h; Inert atmosphere;

DOI:10.1021/acs.orglett.9b03046

upstream raw materials:

2-methyl-1-buten-4-ol

2-[(2-iodophenyl)methyl]propanedioic acid 1,3-dimethyl ester

Downstream raw materials:

(E)-1-(4-methoxystyryl)-1-methyl-3,3-di(methoxycarbonyl)-1,2,3,4-tetrahydronaphthalene