4-carboxy-2-(7-(dimethylamino)-3-(dimethyliminio)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)benzoate

Base Information

• Chemical Name: 4-carboxy-2-(7-(dimethylamino)-3-(dimethyliminio)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)benzoate
• CAS No.: 1418275-26-9
• Molecular Formula: C₂₇H₂₈N₂O₄Si
• Molecular Weight: 472.616
• Mol file: 1418275-26-9.mol

Synonyms:4-carboxy-2-(7-(dimethylamino)-3-(dimethyliminio)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)benzoate

Chemical Property of 4-carboxy-2-(7-(dimethylamino)-3-(dimethyliminio)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-carboxy-2-(7-(dimethylamino)-3-(dimethyliminio)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)benzoate

There total 16 articles about 4-carboxy-2-(7-(dimethylamino)-3-(dimethyliminio)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

3,3'-(dimethylsilanediyl)bis(4-bromo-N,N-dimethylaniline) + ethyl 2,5-bis(4’,4’-dimethyl-4’,5’-dihydrooxazol-2’-yl)benzoate → 4-carboxy-2-(7-(dimethylamino)-3-(dimethyliminio)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)benzoate (1418275-26-9)

Guidance literature:

3,3'-(dimethylsilanediyl)bis(4-bromo-N,N-dimethylaniline); With tert.-butyl lithium; In tetrahydrofuran; at -78 ℃; for 0.5h; Inert atmosphere;

ethyl 2,5-bis(4’,4’-dimethyl-4’,5’-dihydrooxazol-2’-yl)benzoate; In tetrahydrofuran; at -78 - 20 ℃; for 17h; Inert atmosphere;

With hydrogenchloride; In water; at 90 ℃; for 24h; Reagent/catalyst;

DOI:10.1039/d0ob02016h

Reference yield: 35.0%

3,7-bis(N,N-dimethylamino)-5,5-dimethyldibenzo[b,e]silin-10(5H)-one (1290536-55-8) + 1,1'-(2-bromo-1,4-phenylene)bis(4-methyl-2,6,7-trioxabicyclo[2.2.2]octane) → 4-carboxy-2-(7-(dimethylamino)-3-(dimethyliminio)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)benzoate (1418275-26-9)

Guidance literature:

1,1'-(2-bromo-1,4-phenylene)bis(4-methyl-2,6,7-trioxabicyclo[2.2.2]octane); With sec.-butyllithium; In tetrahydrofuran; hexane; cyclohexane; at -78 ℃; for 1h; Inert atmosphere;

3,7-bis(N,N-dimethylamino)-5,5-dimethyldibenzo[b,e]silin-10(5H)-one; In tetrahydrofuran; hexane; cyclohexane; at -78 - 20 ℃; for 3.5h; Inert atmosphere;

With hydrogenchloride; In water; Reflux;

DOI:10.1002/anie.201914826

Reference yield:

C35H43N4O2Si(1+)*C2H3O2(1-) (1418275-25-8) → 4-carboxy-2-(7-(dimethylamino)-3-(dimethyliminio)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)benzoate (1418275-26-9)

Guidance literature:

With hydrogenchloride; water; at 80 ℃;

upstream raw materials:

N³, N³, N⁷, N⁷5,5-hexamethyl-5,10-dihydrodibenzo[b,e]siline-3,7-diamine

3,7-bis(N,N-dimethylamino)-5,5-dimethyldibenzo[b,e]silin-10(5H)-one

2-bromo-1,4-benzenedicarboxylic acid

2-bromobenzene-1,4-dicarbonyl dichloride

Downstream raw materials:

C₄₇H₄₅FN₆O₅Si